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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GOT1
All Species:
47.27
Human Site:
S297
Identified Species:
80
UniProt:
P17174
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P17174
NP_002070.1
413
46248
S297
K
I
V
R
I
T
W
S
N
P
P
A
Q
G
A
Chimpanzee
Pan troglodytes
A5A6K8
413
46215
S297
K
I
V
R
I
T
W
S
N
P
P
A
Q
G
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543963
413
46395
S297
K
I
V
R
I
T
W
S
N
P
P
A
Q
G
A
Cat
Felis silvestris
Mouse
Mus musculus
P05201
413
46213
S297
K
I
V
R
I
T
W
S
N
P
P
A
Q
G
A
Rat
Rattus norvegicus
P13221
413
46410
S297
K
I
V
R
I
T
W
S
N
P
P
A
Q
G
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507985
380
42638
N265
S
K
N
F
G
L
Y
N
E
R
V
G
N
L
T
Chicken
Gallus gallus
P00504
412
45917
S296
K
I
V
R
T
T
W
S
N
P
P
S
Q
G
A
Frog
Xenopus laevis
NP_001080543
411
46052
S295
K
I
V
R
T
T
W
S
N
P
P
S
Q
G
A
Zebra Danio
Brachydanio rerio
NP_998222
410
45964
S294
K
I
V
R
I
T
W
S
N
P
P
S
Q
G
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611086
416
46069
S289
L
L
I
R
G
Q
Y
S
N
P
P
A
Y
G
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22067
408
45475
S289
L
V
I
R
A
N
W
S
N
P
P
A
H
G
A
Sea Urchin
Strong. purpuratus
XP_794016
614
68362
S493
K
L
A
R
A
L
W
S
N
P
P
N
H
G
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P46644
449
48936
S333
L
V
I
R
P
M
Y
S
S
P
P
I
H
G
A
Baker's Yeast
Sacchar. cerevisiae
P23542
418
46039
S297
K
I
I
R
S
E
V
S
N
P
P
A
Y
G
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
N.A.
92.4
N.A.
91
90.3
N.A.
76
80.1
79.9
76.5
N.A.
55.2
N.A.
54.2
39.9
Protein Similarity:
100
100
N.A.
96.6
N.A.
96.3
95.6
N.A.
84.5
89.5
89.5
88.1
N.A.
70.9
N.A.
68.2
50.6
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
0
86.6
86.6
93.3
N.A.
53.3
N.A.
60
60
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
13.3
93.3
93.3
100
N.A.
73.3
N.A.
73.3
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
45.8
46.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
63.4
62.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
66.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
15
0
0
0
0
0
0
58
0
0
93
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
8
0
0
8
0
0
0
0
0
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
15
0
0
0
0
0
0
8
0
93
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
22
0
0
% H
% Ile:
0
65
29
0
43
0
0
0
0
0
0
8
0
0
0
% I
% Lys:
72
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
22
15
0
0
0
15
0
0
0
0
0
0
0
8
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
8
0
8
86
0
0
8
8
0
0
% N
% Pro:
0
0
0
0
8
0
0
0
0
93
93
0
0
0
0
% P
% Gln:
0
0
0
0
0
8
0
0
0
0
0
0
58
0
0
% Q
% Arg:
0
0
0
93
0
0
0
0
0
8
0
0
0
0
0
% R
% Ser:
8
0
0
0
8
0
0
93
8
0
0
22
0
0
0
% S
% Thr:
0
0
0
0
15
58
0
0
0
0
0
0
0
0
8
% T
% Val:
0
15
58
0
0
0
8
0
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
72
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
22
0
0
0
0
0
15
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _