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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GOT1
All Species:
38.48
Human Site:
Y243
Identified Species:
65.13
UniProt:
P17174
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P17174
NP_002070.1
413
46248
Y243
R
D
A
W
A
I
R
Y
F
V
S
E
G
F
E
Chimpanzee
Pan troglodytes
A5A6K8
413
46215
Y243
R
D
A
W
A
I
R
Y
F
V
S
E
G
F
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543963
413
46395
Y243
K
D
A
W
A
V
R
Y
F
V
S
E
G
F
E
Cat
Felis silvestris
Mouse
Mus musculus
P05201
413
46213
Y243
K
D
A
W
A
I
R
Y
F
V
S
E
G
F
E
Rat
Rattus norvegicus
P13221
413
46410
Y243
K
D
A
W
A
I
R
Y
F
V
S
E
G
F
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507985
380
42638
D211
D
Q
W
K
Q
I
A
D
V
M
K
R
R
F
L
Chicken
Gallus gallus
P00504
412
45917
Y242
K
D
A
W
A
V
R
Y
F
V
S
E
G
F
E
Frog
Xenopus laevis
NP_001080543
411
46052
F241
K
D
A
W
A
V
R
F
F
V
S
Q
G
F
E
Zebra Danio
Brachydanio rerio
NP_998222
410
45964
Y240
K
D
A
W
A
V
R
Y
F
V
S
Q
G
F
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611086
416
46069
Y235
R
D
A
W
A
A
R
Y
F
V
Q
R
G
F
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22067
408
45475
Y235
A
D
A
W
A
I
R
Y
F
V
D
Q
G
M
E
Sea Urchin
Strong. purpuratus
XP_794016
614
68362
Y439
K
D
R
W
P
V
Q
Y
F
V
D
Q
G
F
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P46644
449
48936
M279
T
D
A
K
P
I
R
M
F
V
A
D
G
G
E
Baker's Yeast
Sacchar. cerevisiae
P23542
418
46039
T243
L
G
V
E
K
L
S
T
V
S
P
V
F
V
C
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
N.A.
92.4
N.A.
91
90.3
N.A.
76
80.1
79.9
76.5
N.A.
55.2
N.A.
54.2
39.9
Protein Similarity:
100
100
N.A.
96.6
N.A.
96.3
95.6
N.A.
84.5
89.5
89.5
88.1
N.A.
70.9
N.A.
68.2
50.6
P-Site Identity:
100
100
N.A.
86.6
N.A.
93.3
93.3
N.A.
13.3
86.6
73.3
80
N.A.
80
N.A.
73.3
53.3
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
20
100
100
100
N.A.
80
N.A.
80
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
45.8
46.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
63.4
62.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
53.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
79
0
72
8
8
0
0
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
8
86
0
0
0
0
0
8
0
0
15
8
0
0
0
% D
% Glu:
0
0
0
8
0
0
0
0
0
0
0
43
0
0
86
% E
% Phe:
0
0
0
0
0
0
0
8
86
0
0
0
8
79
0
% F
% Gly:
0
8
0
0
0
0
0
0
0
0
0
0
86
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
50
0
0
0
0
0
0
0
0
0
% I
% Lys:
50
0
0
15
8
0
0
0
0
0
8
0
0
0
0
% K
% Leu:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
8
0
8
0
0
0
8
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
15
0
0
0
0
0
8
0
0
0
0
% P
% Gln:
0
8
0
0
8
0
8
0
0
0
8
29
0
0
0
% Q
% Arg:
22
0
8
0
0
0
79
0
0
0
0
15
8
0
0
% R
% Ser:
0
0
0
0
0
0
8
0
0
8
58
0
0
0
0
% S
% Thr:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% T
% Val:
0
0
8
0
0
36
0
0
15
86
0
8
0
8
0
% V
% Trp:
0
0
8
79
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
72
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _