KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GOT1
All Species:
30.91
Human Site:
Y373
Identified Species:
52.31
UniProt:
P17174
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P17174
NP_002070.1
413
46248
Y373
L
N
P
K
Q
V
E
Y
L
V
N
E
K
H
I
Chimpanzee
Pan troglodytes
A5A6K8
413
46215
Y373
L
N
P
K
Q
V
E
Y
L
V
N
E
K
H
I
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543963
413
46395
Y373
L
N
P
K
Q
V
E
Y
L
V
N
E
K
H
I
Cat
Felis silvestris
Mouse
Mus musculus
P05201
413
46213
Y373
L
N
P
K
Q
V
E
Y
L
V
N
E
K
H
I
Rat
Rattus norvegicus
P13221
413
46410
Y373
L
N
P
K
Q
V
E
Y
L
V
N
E
K
H
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507985
380
42638
R341
M
R
S
E
L
R
A
R
L
E
A
L
R
T
P
Chicken
Gallus gallus
P00504
412
45917
Y372
L
N
P
K
Q
V
E
Y
M
I
K
E
K
H
I
Frog
Xenopus laevis
NP_001080543
411
46052
Y371
L
N
P
K
Q
V
E
Y
L
I
K
E
K
H
I
Zebra Danio
Brachydanio rerio
NP_998222
410
45964
Y370
L
N
P
K
Q
V
E
Y
M
I
K
E
K
H
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611086
416
46069
V365
L
N
E
S
H
V
R
V
L
I
D
Q
Y
H
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22067
408
45475
H365
L
T
S
A
Q
V
D
H
L
I
A
N
H
K
V
Sea Urchin
Strong. purpuratus
XP_794016
614
68362
F569
L
G
P
K
Q
M
T
F
L
K
E
K
Y
H
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P46644
449
48936
F409
L
N
P
A
Q
V
S
F
M
T
K
E
Y
H
I
Baker's Yeast
Sacchar. cerevisiae
P23542
418
46039
R373
L
T
P
Q
M
V
K
R
L
E
E
T
H
A
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
N.A.
92.4
N.A.
91
90.3
N.A.
76
80.1
79.9
76.5
N.A.
55.2
N.A.
54.2
39.9
Protein Similarity:
100
100
N.A.
96.6
N.A.
96.3
95.6
N.A.
84.5
89.5
89.5
88.1
N.A.
70.9
N.A.
68.2
50.6
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
6.6
80
86.6
80
N.A.
40
N.A.
26.6
46.6
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
26.6
93.3
93.3
93.3
N.A.
60
N.A.
53.3
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
45.8
46.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
63.4
62.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
53.3
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
15
0
0
8
0
0
0
15
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
0
0
8
0
0
0
0
% D
% Glu:
0
0
8
8
0
0
58
0
0
15
15
65
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
8
0
0
8
0
0
0
0
15
79
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
36
0
0
0
0
79
% I
% Lys:
0
0
0
65
0
0
8
0
0
8
29
8
58
8
0
% K
% Leu:
93
0
0
0
8
0
0
0
79
0
0
8
0
0
0
% L
% Met:
8
0
0
0
8
8
0
0
22
0
0
0
0
0
0
% M
% Asn:
0
72
0
0
0
0
0
0
0
0
36
8
0
0
0
% N
% Pro:
0
0
79
0
0
0
0
0
0
0
0
0
0
0
8
% P
% Gln:
0
0
0
8
79
0
0
0
0
0
0
8
0
0
0
% Q
% Arg:
0
8
0
0
0
8
8
15
0
0
0
0
8
0
0
% R
% Ser:
0
0
15
8
0
0
8
0
0
0
0
0
0
0
0
% S
% Thr:
0
15
0
0
0
0
8
0
0
8
0
8
0
8
0
% T
% Val:
0
0
0
0
0
86
0
8
0
36
0
0
0
0
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
58
0
0
0
0
22
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _