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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GJA1 All Species: 31.82
Human Site: Y98 Identified Species: 77.78
UniProt: P17302 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P17302 NP_000156.1 382 43008 Y98 L Y L A H V F Y V M R K E E K
Chimpanzee Pan troglodytes XP_001164302 382 43020 Y98 L Y L A H V F Y V M R K E E K
Rhesus Macaque Macaca mulatta XP_001109566 382 43034 Y98 L Y L A H V F Y V M R K E E K
Dog Lupus familis XP_539602 333 37317 D67 G C T N V C Y D Q A F P I S H
Cat Felis silvestris
Mouse Mus musculus P23242 382 42986 Y98 L Y L A H V F Y V M R K E E K
Rat Rattus norvegicus P08050 382 43013 Y98 L Y L A H V F Y V M R K E E K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508248 340 38783 H74 D K S F P I S H V R F W V L Q
Chicken Gallus gallus P14154 381 43107 Y98 L Y L A H V F Y V M R K E E K
Frog Xenopus laevis P16863 379 42943 Y98 L Y L A H V F Y L M R K E E K
Zebra Danio Brachydanio rerio O57474 381 43436 Y98 L Y L A H V F Y L M R K E E K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 99.4 44.7 N.A. 97.3 97.6 N.A. 70.1 93.4 86.1 80.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.7 99.7 60.4 N.A. 99.4 99.4 N.A. 75.9 97.3 93.4 89 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 0 N.A. 100 100 N.A. 6.6 100 93.3 93.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 6.6 N.A. 100 100 N.A. 26.6 100 100 100 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 80 0 0 0 0 0 10 0 0 0 0 0 % A
% Cys: 0 10 0 0 0 10 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 80 80 0 % E
% Phe: 0 0 0 10 0 0 80 0 0 0 20 0 0 0 0 % F
% Gly: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 80 0 0 10 0 0 0 0 0 0 10 % H
% Ile: 0 0 0 0 0 10 0 0 0 0 0 0 10 0 0 % I
% Lys: 0 10 0 0 0 0 0 0 0 0 0 80 0 0 80 % K
% Leu: 80 0 80 0 0 0 0 0 20 0 0 0 0 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 80 0 0 0 0 0 % M
% Asn: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 10 0 0 0 0 0 0 10 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 10 % Q
% Arg: 0 0 0 0 0 0 0 0 0 10 80 0 0 0 0 % R
% Ser: 0 0 10 0 0 0 10 0 0 0 0 0 0 10 0 % S
% Thr: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 10 80 0 0 70 0 0 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % W
% Tyr: 0 80 0 0 0 0 10 80 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _