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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NPR3 All Species: 4.55
Human Site: T516 Identified Species: 12.5
UniProt: P17342 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P17342 NP_000899.1 541 59808 T516 R I T I E R R T Q Q E E S N L
Chimpanzee Pan troglodytes XP_526959 540 59778 T515 R I T I E R R T Q Q E E S N L
Rhesus Macaque Macaca mulatta XP_001087354 540 59792 N515 R I T I E R R N Q Q E E S N L
Dog Lupus familis XP_536511 764 81750 R740 R E P R L P G R L C G R S P A
Cat Felis silvestris
Mouse Mus musculus P70180 536 59823 N511 R I T I E R R N Q Q E E S N I
Rat Rattus norvegicus P41740 535 59709 N510 R I T I E R R N H Q E E S N I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507606 281 31783 Q257 I T I E R R T Q Q E E S N I G
Chicken Gallus gallus
Frog Xenopus laevis NP_001084234 507 57234 N482 R I T I E R R N Q Q D D C N L
Zebra Danio Brachydanio rerio NP_001096143 472 53389 L448 I T I E R R T L R E E C D I G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 98.1 34.6 N.A. 90.5 90.9 N.A. 48 N.A. 68.2 49.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.4 98.7 40 N.A. 92.7 92.9 N.A. 50.4 N.A. 80.7 63.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 13.3 N.A. 86.6 80 N.A. 20 N.A. 73.3 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 93.3 13.3 N.A. 93.3 86.6 N.A. 33.3 N.A. 86.6 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % A
% Cys: 0 0 0 0 0 0 0 0 0 12 0 12 12 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 12 12 12 0 0 % D
% Glu: 0 12 0 23 67 0 0 0 0 23 78 56 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 12 0 0 0 12 0 0 0 23 % G
% His: 0 0 0 0 0 0 0 0 12 0 0 0 0 0 0 % H
% Ile: 23 67 23 67 0 0 0 0 0 0 0 0 0 23 23 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 12 0 0 12 12 0 0 0 0 0 45 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 45 0 0 0 0 12 67 0 % N
% Pro: 0 0 12 0 0 12 0 0 0 0 0 0 0 12 0 % P
% Gln: 0 0 0 0 0 0 0 12 67 67 0 0 0 0 0 % Q
% Arg: 78 0 0 12 23 89 67 12 12 0 0 12 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 12 67 0 0 % S
% Thr: 0 23 67 0 0 0 23 23 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _