KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HOXB4
All Species:
46.97
Human Site:
Y186
Identified Species:
86.11
UniProt:
P17483
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P17483
NP_076920.1
251
27604
Y186
K
E
F
H
Y
N
R
Y
L
T
R
R
R
R
V
Chimpanzee
Pan troglodytes
XP_001173043
251
27527
Y186
K
E
F
H
Y
N
R
Y
L
T
R
R
R
R
V
Rhesus Macaque
Macaca mulatta
XP_001094862
255
27890
Y178
K
E
F
H
F
N
R
Y
L
T
R
R
R
R
I
Dog
Lupus familis
XP_851159
459
50638
Y312
K
E
F
H
Y
N
R
Y
L
T
R
R
R
R
V
Cat
Felis silvestris
Mouse
Mus musculus
P10284
250
27501
Y185
K
E
F
H
Y
N
R
Y
L
T
R
R
R
R
V
Rat
Rattus norvegicus
NP_001094257
250
27519
Y185
K
E
F
H
Y
N
R
Y
L
T
R
R
R
R
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509234
335
37537
Y176
K
E
F
H
Y
N
R
Y
L
T
R
R
R
R
V
Chicken
Gallus gallus
P14840
245
27764
Y174
K
E
F
H
Y
N
R
Y
L
T
R
R
R
R
V
Frog
Xenopus laevis
P09070
232
26449
T167
F
H
Y
N
R
Y
L
T
R
R
R
R
V
E
I
Zebra Danio
Brachydanio rerio
P22574
246
27686
Y175
K
E
F
H
Y
N
R
Y
L
T
R
R
R
R
V
Tiger Blowfish
Takifugu rubipres
O13074
288
32704
Y184
K
E
F
H
Y
N
R
Y
L
T
R
R
R
R
V
Fruit Fly
Dros. melanogaster
P07548
586
63362
Y390
K
E
F
H
Y
N
R
Y
L
T
R
R
R
R
I
Honey Bee
Apis mellifera
P15860
74
9244
E26
Q
T
L
E
L
E
K
E
F
H
Y
N
R
Y
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
54.5
39.4
N.A.
95.6
94.8
N.A.
59
67.3
54.5
63.7
54.8
23.5
25.1
N.A.
N.A.
Protein Similarity:
100
99.5
62.3
44.6
N.A.
96
95.2
N.A.
62.3
75.6
60.5
74
61.8
29.5
27.8
N.A.
N.A.
P-Site Identity:
100
100
86.6
100
N.A.
100
100
N.A.
100
100
13.3
100
100
93.3
6.6
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
33.3
100
100
100
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
85
0
8
0
8
0
8
0
0
0
0
0
8
0
% E
% Phe:
8
0
85
0
8
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
8
0
85
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
24
% I
% Lys:
85
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
8
0
8
0
8
0
85
0
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
85
0
0
0
0
0
8
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
8
0
85
0
8
8
93
93
93
85
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
8
0
0
0
0
0
8
0
85
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
70
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
77
8
0
85
0
0
8
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _