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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TAL1 All Species: 20.91
Human Site: S122 Identified Species: 41.82
UniProt: P17542 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P17542 NP_003180.1 331 34271 S122 D G R M V Q L S P P A L A A P
Chimpanzee Pan troglodytes XP_001163354 331 34278 S122 D G R M V Q L S P P A L A A P
Rhesus Macaque Macaca mulatta XP_001088653 148 14676
Dog Lupus familis XP_852903 327 33732 S118 D G R M V Q L S P P A L A A P
Cat Felis silvestris
Mouse Mus musculus P22091 329 34260 S122 D G R M V Q L S P P A L A A P
Rat Rattus norvegicus Q66HH3 278 29939 L101 T A P P T L A L H Y H P H P F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518368 179 19831
Chicken Gallus gallus P24899 311 33749 S116 E A R M V Q L S P P A L P L Q
Frog Xenopus laevis O73823 394 43024 S197 E A R M V Q L S P T A S L P L
Zebra Danio Brachydanio rerio O93507 324 35687 R118 R D P L S D T R M V Q L S P P
Tiger Blowfish Takifugu rubipres Q90YI8 371 40876 V144 Q R D D A R M V Q L S P N A F
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792477 400 43713 T163 F S P Q V T W T F P T A V N P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 41.9 92.7 N.A. 93 35.3 N.A. 41.6 56.1 49.4 50.7 38.5 N.A. N.A. N.A. 25.7
Protein Similarity: 100 99.6 42.2 93.6 N.A. 94.5 44.4 N.A. 45.3 62.8 56.8 61 50.9 N.A. N.A. N.A. 39.7
P-Site Identity: 100 100 0 100 N.A. 100 0 N.A. 0 66.6 53.3 13.3 6.6 N.A. N.A. N.A. 20
P-Site Similarity: 100 100 0 100 N.A. 100 0 N.A. 0 73.3 60 26.6 26.6 N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 25 0 0 9 0 9 0 0 0 50 9 34 42 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 34 9 9 9 0 9 0 0 0 0 0 0 0 0 0 % D
% Glu: 17 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 9 0 0 0 0 0 0 0 9 0 0 0 0 0 17 % F
% Gly: 0 34 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 9 0 9 0 9 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 9 0 9 50 9 0 9 0 50 9 9 9 % L
% Met: 0 0 0 50 0 0 9 0 9 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 9 9 0 % N
% Pro: 0 0 25 9 0 0 0 0 50 50 0 17 9 25 50 % P
% Gln: 9 0 0 9 0 50 0 0 9 0 9 0 0 0 9 % Q
% Arg: 9 9 50 0 0 9 0 9 0 0 0 0 0 0 0 % R
% Ser: 0 9 0 0 9 0 0 50 0 0 9 9 9 0 0 % S
% Thr: 9 0 0 0 9 9 9 9 0 9 9 0 0 0 0 % T
% Val: 0 0 0 0 59 0 0 9 0 9 0 0 9 0 0 % V
% Trp: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _