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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TAL1
All Species:
20
Human Site:
S149
Identified Species:
40
UniProt:
P17542
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P17542
NP_003180.1
331
34271
S149
Q
P
L
A
S
L
G
S
G
F
F
G
E
P
D
Chimpanzee
Pan troglodytes
XP_001163354
331
34278
S149
Q
P
L
A
S
L
G
S
G
F
F
G
E
P
D
Rhesus Macaque
Macaca mulatta
XP_001088653
148
14676
Dog
Lupus familis
XP_852903
327
33732
F145
Q
P
G
G
A
C
G
F
G
F
F
G
E
P
D
Cat
Felis silvestris
Mouse
Mus musculus
P22091
329
34260
S149
Q
P
L
A
S
L
G
S
G
F
F
G
E
P
D
Rat
Rattus norvegicus
Q66HH3
278
29939
R127
F
S
I
F
P
N
S
R
L
K
R
R
P
S
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518368
179
19831
R28
N
N
N
R
V
K
R
R
P
S
P
Y
E
V
E
Chicken
Gallus gallus
P24899
311
33749
S142
Q
P
L
G
T
I
G
S
G
F
F
G
E
P
D
Frog
Xenopus laevis
O73823
394
43024
S224
Q
P
L
A
S
D
N
S
G
Y
F
G
D
P
D
Zebra Danio
Brachydanio rerio
O93507
324
35687
N147
T
T
P
L
A
T
I
N
S
G
F
A
G
D
A
Tiger Blowfish
Takifugu rubipres
Q90YI8
371
40876
S171
Q
P
L
A
A
I
N
S
L
G
G
E
S
E
Q
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792477
400
43713
T191
P
Q
P
H
Q
A
P
T
N
P
H
Q
Q
T
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
41.9
92.7
N.A.
93
35.3
N.A.
41.6
56.1
49.4
50.7
38.5
N.A.
N.A.
N.A.
25.7
Protein Similarity:
100
99.6
42.2
93.6
N.A.
94.5
44.4
N.A.
45.3
62.8
56.8
61
50.9
N.A.
N.A.
N.A.
39.7
P-Site Identity:
100
100
0
66.6
N.A.
100
0
N.A.
6.6
80
73.3
6.6
33.3
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
0
73.3
N.A.
100
6.6
N.A.
13.3
93.3
86.6
20
46.6
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
42
25
9
0
0
0
0
0
9
0
0
9
% A
% Cys:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
9
0
0
0
0
0
0
9
9
50
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
9
50
9
9
% E
% Phe:
9
0
0
9
0
0
0
9
0
42
59
0
0
0
9
% F
% Gly:
0
0
9
17
0
0
42
0
50
17
9
50
9
0
0
% G
% His:
0
0
0
9
0
0
0
0
0
0
9
0
0
0
9
% H
% Ile:
0
0
9
0
0
17
9
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
9
0
0
0
9
0
0
0
0
0
% K
% Leu:
0
0
50
9
0
25
0
0
17
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
9
9
0
0
9
17
9
9
0
0
0
0
0
0
% N
% Pro:
9
59
17
0
9
0
9
0
9
9
9
0
9
50
0
% P
% Gln:
59
9
0
0
9
0
0
0
0
0
0
9
9
0
9
% Q
% Arg:
0
0
0
9
0
0
9
17
0
0
9
9
0
0
0
% R
% Ser:
0
9
0
0
34
0
9
50
9
9
0
0
9
9
0
% S
% Thr:
9
9
0
0
9
9
0
9
0
0
0
0
0
9
0
% T
% Val:
0
0
0
0
9
0
0
0
0
0
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
9
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _