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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TAL1 All Species: 30.61
Human Site: S300 Identified Species: 61.21
UniProt: P17542 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P17542 NP_003180.1 331 34271 S300 S S L D G A A S P D S Y T E E
Chimpanzee Pan troglodytes XP_001163354 331 34278 S300 S S L D G A A S P D S Y T E E
Rhesus Macaque Macaca mulatta XP_001088653 148 14676 A125 M V Q L S P P A L A A P A A P
Dog Lupus familis XP_852903 327 33732 S296 S S L D G A A S P D S Y T E E
Cat Felis silvestris
Mouse Mus musculus P22091 329 34260 S298 S S L D G A A S P D S Y T E E
Rat Rattus norvegicus Q66HH3 278 29939 C255 Q P V L P G D C D G D P N G S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518368 179 19831 E156 D S F S E E A E A L D A K H P
Chicken Gallus gallus P24899 311 33749 S279 S S L D G A A S P D S F T E E
Frog Xenopus laevis O73823 394 43024 S362 S S L D G A P S P D S Y S E E
Zebra Danio Brachydanio rerio O93507 324 35687 S290 S L L D G D A S P E S F T E D
Tiger Blowfish Takifugu rubipres Q90YI8 371 40876 S326 P D G D A D G S P E S F M E D
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792477 400 43713 S345 P V R N R A R S S R S S S E S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 41.9 92.7 N.A. 93 35.3 N.A. 41.6 56.1 49.4 50.7 38.5 N.A. N.A. N.A. 25.7
Protein Similarity: 100 99.6 42.2 93.6 N.A. 94.5 44.4 N.A. 45.3 62.8 56.8 61 50.9 N.A. N.A. N.A. 39.7
P-Site Identity: 100 100 0 100 N.A. 100 0 N.A. 13.3 93.3 86.6 66.6 33.3 N.A. N.A. N.A. 26.6
P-Site Similarity: 100 100 13.3 100 N.A. 100 6.6 N.A. 13.3 100 93.3 86.6 53.3 N.A. N.A. N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 9 59 59 9 9 9 9 9 9 9 0 % A
% Cys: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % C
% Asp: 9 9 0 67 0 17 9 0 9 50 17 0 0 0 17 % D
% Glu: 0 0 0 0 9 9 0 9 0 17 0 0 0 75 50 % E
% Phe: 0 0 9 0 0 0 0 0 0 0 0 25 0 0 0 % F
% Gly: 0 0 9 0 59 9 9 0 0 9 0 0 0 9 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % K
% Leu: 0 9 59 17 0 0 0 0 9 9 0 0 0 0 0 % L
% Met: 9 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % M
% Asn: 0 0 0 9 0 0 0 0 0 0 0 0 9 0 0 % N
% Pro: 17 9 0 0 9 9 17 0 67 0 0 17 0 0 17 % P
% Gln: 9 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 9 0 9 0 9 0 0 9 0 0 0 0 0 % R
% Ser: 59 59 0 9 9 0 0 75 9 0 75 9 17 0 17 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 50 0 0 % T
% Val: 0 17 9 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 42 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _