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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TAL1 All Species: 17.88
Human Site: Y174 Identified Species: 35.76
UniProt: P17542 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P17542 NP_003180.1 331 34271 Y174 V K R R P S P Y E M E I T D G
Chimpanzee Pan troglodytes XP_001163354 331 34278 Y174 V K R R P S P Y E M E I T D G
Rhesus Macaque Macaca mulatta XP_001088653 148 14676 A21 P Q L E G R D A A E A R M A P
Dog Lupus familis XP_852903 327 33732 Y170 V K R R P S P Y E M E I T D G
Cat Felis silvestris
Mouse Mus musculus P22091 329 34260 Y174 V K R R P S P Y E M E I S D G
Rat Rattus norvegicus Q66HH3 278 29939 V152 P Q K V A R R V F T N S R E R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518368 179 19831 R53 R R I F T N T R E R W R Q Q N
Chicken Gallus gallus P24899 311 33749 E167 K R R P S P Y E M E I T D G P
Frog Xenopus laevis O73823 394 43024 I249 A K R R P G P I E V E I S E G
Zebra Danio Brachydanio rerio O93507 324 35687 Y172 V K R R P A P Y E V E I N D G
Tiger Blowfish Takifugu rubipres Q90YI8 371 40876 V196 R R P A P Y E V E L D E A K I
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792477 400 43713 H216 H L P R Q A M H A P V L E R V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 41.9 92.7 N.A. 93 35.3 N.A. 41.6 56.1 49.4 50.7 38.5 N.A. N.A. N.A. 25.7
Protein Similarity: 100 99.6 42.2 93.6 N.A. 94.5 44.4 N.A. 45.3 62.8 56.8 61 50.9 N.A. N.A. N.A. 39.7
P-Site Identity: 100 100 0 100 N.A. 93.3 0 N.A. 6.6 6.6 60 80 13.3 N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 6.6 100 N.A. 100 20 N.A. 20 13.3 80 93.3 33.3 N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 9 9 17 0 9 17 0 9 0 9 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 9 0 0 0 9 0 9 42 0 % D
% Glu: 0 0 0 9 0 0 9 9 67 17 50 9 9 17 0 % E
% Phe: 0 0 0 9 0 0 0 0 9 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 9 9 0 0 0 0 0 0 0 9 50 % G
% His: 9 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % H
% Ile: 0 0 9 0 0 0 0 9 0 0 9 50 0 0 9 % I
% Lys: 9 50 9 0 0 0 0 0 0 0 0 0 0 9 0 % K
% Leu: 0 9 9 0 0 0 0 0 0 9 0 9 0 0 0 % L
% Met: 0 0 0 0 0 0 9 0 9 34 0 0 9 0 0 % M
% Asn: 0 0 0 0 0 9 0 0 0 0 9 0 9 0 9 % N
% Pro: 17 0 17 9 59 9 50 0 0 9 0 0 0 0 17 % P
% Gln: 0 17 0 0 9 0 0 0 0 0 0 0 9 9 0 % Q
% Arg: 17 25 59 59 0 17 9 9 0 9 0 17 9 9 9 % R
% Ser: 0 0 0 0 9 34 0 0 0 0 0 9 17 0 0 % S
% Thr: 0 0 0 0 9 0 9 0 0 9 0 9 25 0 0 % T
% Val: 42 0 0 9 0 0 0 17 0 17 9 0 0 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % W
% Tyr: 0 0 0 0 0 9 9 42 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _