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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SYN1
All Species:
10.91
Human Site:
S149
Identified Species:
30
UniProt:
P17600
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P17600
NP_008881.2
705
74111
S149
K
V
E
Q
A
E
F
S
D
L
N
L
V
A
H
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001086745
582
63133
K114
P
A
A
A
R
K
A
K
V
L
L
V
V
D
E
Dog
Lupus familis
XP_538411
578
63013
G110
D
W
T
K
Y
F
H
G
K
K
V
N
G
E
I
Cat
Felis silvestris
Mouse
Mus musculus
O88935
706
74079
S149
K
V
E
Q
A
E
F
S
D
L
N
L
V
A
H
Rat
Rattus norvegicus
P09951
704
73970
S149
K
V
E
Q
A
E
F
S
D
L
N
L
V
A
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510384
582
63180
T114
K
Y
F
H
A
K
R
T
N
G
E
L
E
I
R
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001087750
655
71582
V149
S
F
S
V
D
L
E
V
L
R
N
G
V
K
V
Zebra Danio
Brachydanio rerio
NP_001119909
670
72335
A145
S
Y
S
V
D
I
E
A
I
R
S
G
N
K
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24546
1025
107509
R169
R
V
E
Q
A
E
F
R
D
I
T
V
V
S
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
56.5
53
N.A.
96.1
96.1
N.A.
51
N.A.
60.9
61.8
N.A.
28.8
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
66.5
64.6
N.A.
97
96.8
N.A.
63.1
N.A.
68.5
70.9
N.A.
41.3
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
13.3
0
N.A.
100
100
N.A.
20
N.A.
13.3
0
N.A.
53.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
26.6
6.6
N.A.
100
100
N.A.
40
N.A.
13.3
13.3
N.A.
80
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
12
12
56
0
12
12
0
0
0
0
0
34
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
0
0
0
23
0
0
0
45
0
0
0
0
12
0
% D
% Glu:
0
0
45
0
0
45
23
0
0
0
12
0
12
12
12
% E
% Phe:
0
12
12
0
0
12
45
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
12
0
12
0
23
12
0
0
% G
% His:
0
0
0
12
0
0
12
0
0
0
0
0
0
0
34
% H
% Ile:
0
0
0
0
0
12
0
0
12
12
0
0
0
12
23
% I
% Lys:
45
0
0
12
0
23
0
12
12
12
0
0
0
23
0
% K
% Leu:
0
0
0
0
0
12
0
0
12
45
12
45
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
12
0
45
12
12
0
0
% N
% Pro:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
45
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
12
0
0
0
12
0
12
12
0
23
0
0
0
0
12
% R
% Ser:
23
0
23
0
0
0
0
34
0
0
12
0
0
12
12
% S
% Thr:
0
0
12
0
0
0
0
12
0
0
12
0
0
0
0
% T
% Val:
0
45
0
23
0
0
0
12
12
0
12
23
67
0
12
% V
% Trp:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
23
0
0
12
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _