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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKACA
All Species:
20.91
Human Site:
S15
Identified Species:
41.82
UniProt:
P17612
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P17612
NP_002721.1
351
40590
S15
K
K
G
S
E
Q
E
S
V
K
E
F
L
A
K
Chimpanzee
Pan troglodytes
XP_001171437
427
49115
V91
R
R
P
W
P
W
N
V
V
K
E
F
L
A
K
Rhesus Macaque
Macaca mulatta
O62846
209
24077
Dog
Lupus familis
XP_867543
351
40605
S15
K
K
G
S
E
V
E
S
V
K
E
F
L
A
K
Cat
Felis silvestris
Mouse
Mus musculus
P05132
351
40552
S15
K
K
G
S
E
Q
E
S
V
K
E
F
L
A
K
Rat
Rattus norvegicus
P27791
351
40601
S15
K
K
G
S
E
Q
E
S
V
K
E
F
L
A
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422379
398
45968
S62
L
A
V
L
W
D
K
S
M
K
E
F
L
A
K
Frog
Xenopus laevis
Q6GPN6
434
49096
S59
C
K
P
S
E
V
Q
S
I
L
N
I
S
P
P
Zebra Danio
Brachydanio rerio
Q7ZTW4
433
48964
G36
F
M
K
Q
R
K
M
G
L
N
D
F
I
Q
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P12370
353
40820
T17
K
K
V
D
A
A
E
T
V
K
E
F
L
E
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P21137
404
46327
P49
K
L
S
I
L
D
D
P
V
E
D
F
K
E
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P06245
380
44201
N19
G
Q
T
I
Q
Q
Q
N
V
N
T
Y
G
Q
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.5
51.2
93.1
N.A.
98
98
N.A.
N.A.
81.4
35.2
34.8
N.A.
82.4
N.A.
68.5
N.A.
Protein Similarity:
100
81.9
56.7
95.4
N.A.
99.4
99.1
N.A.
N.A.
84.6
54.1
53.1
N.A.
90
N.A.
78.4
N.A.
P-Site Identity:
100
46.6
0
93.3
N.A.
100
100
N.A.
N.A.
46.6
26.6
13.3
N.A.
53.3
N.A.
20
N.A.
P-Site Similarity:
100
60
0
93.3
N.A.
100
100
N.A.
N.A.
60
40
40
N.A.
66.6
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
45.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
67.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
9
9
0
0
0
0
0
0
0
50
0
% A
% Cys:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
0
17
9
0
0
0
17
0
0
0
0
% D
% Glu:
0
0
0
0
42
0
42
0
0
9
59
0
0
17
0
% E
% Phe:
9
0
0
0
0
0
0
0
0
0
0
75
0
0
9
% F
% Gly:
9
0
34
0
0
0
0
9
0
0
0
0
9
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
17
0
0
0
0
9
0
0
9
9
0
0
% I
% Lys:
50
50
9
0
0
9
9
0
0
59
0
0
9
0
59
% K
% Leu:
9
9
0
9
9
0
0
0
9
9
0
0
59
0
0
% L
% Met:
0
9
0
0
0
0
9
0
9
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
9
9
0
17
9
0
0
0
0
% N
% Pro:
0
0
17
0
9
0
0
9
0
0
0
0
0
9
9
% P
% Gln:
0
9
0
9
9
34
17
0
0
0
0
0
0
17
9
% Q
% Arg:
9
9
0
0
9
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
9
42
0
0
0
50
0
0
0
0
9
0
0
% S
% Thr:
0
0
9
0
0
0
0
9
0
0
9
0
0
0
0
% T
% Val:
0
0
17
0
0
17
0
9
67
0
0
0
0
0
0
% V
% Trp:
0
0
0
9
9
9
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _