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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TYRP1 All Species: 25.76
Human Site: S76 Identified Species: 62.96
UniProt: P17643 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P17643 NP_000541.1 537 60724 S76 T A D S R P H S P Q Y P H D G
Chimpanzee Pan troglodytes XP_520488 537 60736 S76 T A D S R P H S P Q Y P H D G
Rhesus Macaque Macaca mulatta XP_001111475 537 60802 S76 T A D S R P H S P R Y P H D G
Dog Lupus familis XP_531934 537 60730 S76 I A D S R P H S H H Y P H D G
Cat Felis silvestris
Mouse Mus musculus P07147 537 60743 S76 I A D S R P H S R H Y P H D G
Rat Rattus norvegicus NP_001100134 537 60433 S76 T A D S R P H S R H Y P H D G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507109 535 60996 S74 N A D S R P H S P Q Y P H D G
Chicken Gallus gallus O57405 535 60577 G75 T V D S R P H G P Q Y I H D G
Frog Xenopus laevis NP_001080492 534 60827 G78 T V D S L P H G P Q Y R L D G
Zebra Danio Brachydanio rerio XP_002663085 521 58337 Y69 T R A H G P Q Y P Y T G R D D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 97.2 89.3 N.A. 85.4 85 N.A. 81.1 75.6 68.3 66.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.6 98.6 93.4 N.A. 91 91.4 N.A. 88.8 86.9 79.8 78.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 80 N.A. 80 86.6 N.A. 93.3 80 66.6 26.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 80 N.A. 80 86.6 N.A. 93.3 80 66.6 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 70 10 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 90 0 0 0 0 0 0 0 0 0 0 100 10 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 10 0 0 20 0 0 0 10 0 0 90 % G
% His: 0 0 0 10 0 0 90 0 10 30 0 0 80 0 0 % H
% Ile: 20 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 10 0 0 0 0 0 0 0 10 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 100 0 0 70 0 0 70 0 0 0 % P
% Gln: 0 0 0 0 0 0 10 0 0 50 0 0 0 0 0 % Q
% Arg: 0 10 0 0 80 0 0 0 20 10 0 10 10 0 0 % R
% Ser: 0 0 0 90 0 0 0 70 0 0 0 0 0 0 0 % S
% Thr: 70 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % T
% Val: 0 20 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 10 0 10 90 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _