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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TYRP1
All Species:
29.39
Human Site:
T53
Identified Species:
71.85
UniProt:
P17643
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P17643
NP_000541.1
537
60724
T53
S
P
V
S
G
P
G
T
D
R
C
G
S
S
S
Chimpanzee
Pan troglodytes
XP_520488
537
60736
T53
S
P
V
S
G
P
G
T
D
R
C
G
S
S
S
Rhesus Macaque
Macaca mulatta
XP_001111475
537
60802
T53
S
P
M
S
G
P
G
T
D
R
C
G
S
S
S
Dog
Lupus familis
XP_531934
537
60730
T53
S
P
V
S
G
P
G
T
D
P
C
G
F
S
S
Cat
Felis silvestris
Mouse
Mus musculus
P07147
537
60743
T53
L
P
S
S
G
P
G
T
D
P
C
G
S
S
S
Rat
Rattus norvegicus
NP_001100134
537
60433
T53
F
P
S
S
G
P
G
T
D
P
C
G
S
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507109
535
60996
T51
F
P
G
A
D
P
G
T
D
K
C
G
S
L
S
Chicken
Gallus gallus
O57405
535
60577
S52
F
P
V
F
G
P
G
S
D
Q
C
G
V
S
T
Frog
Xenopus laevis
NP_001080492
534
60827
T55
P
G
Q
S
P
D
P
T
D
Q
C
G
F
S
L
Zebra Danio
Brachydanio rerio
XP_002663085
521
58337
C46
N
G
L
G
D
D
P
C
G
A
S
L
G
R
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
97.2
89.3
N.A.
85.4
85
N.A.
81.1
75.6
68.3
66.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
98.6
93.4
N.A.
91
91.4
N.A.
88.8
86.9
79.8
78.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
86.6
N.A.
80
80
N.A.
60
60
40
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
80
80
N.A.
73.3
80
46.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
0
0
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
90
0
0
0
0
% C
% Asp:
0
0
0
0
20
20
0
0
90
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
30
0
0
10
0
0
0
0
0
0
0
0
20
0
0
% F
% Gly:
0
20
10
10
70
0
80
0
10
0
0
90
10
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% K
% Leu:
10
0
10
0
0
0
0
0
0
0
0
10
0
10
10
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
80
0
0
10
80
20
0
0
30
0
0
0
0
0
% P
% Gln:
0
0
10
0
0
0
0
0
0
20
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
30
0
0
0
10
0
% R
% Ser:
40
0
20
70
0
0
0
10
0
0
10
0
60
80
70
% S
% Thr:
0
0
0
0
0
0
0
80
0
0
0
0
0
0
10
% T
% Val:
0
0
40
0
0
0
0
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _