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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CAPN2
All Species:
31.21
Human Site:
S250
Identified Species:
68.67
UniProt:
P17655
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P17655
NP_001139540.1
700
80009
S250
D
I
T
S
A
A
D
S
E
A
I
T
F
Q
K
Chimpanzee
Pan troglodytes
XP_001169048
714
81876
M260
D
I
S
S
V
L
D
M
E
A
I
T
F
K
K
Rhesus Macaque
Macaca mulatta
XP_001098172
700
80008
S250
D
I
T
S
A
A
D
S
E
A
I
T
Y
Q
K
Dog
Lupus familis
XP_537240
677
77624
A229
T
S
M
A
D
S
E
A
I
T
F
Q
K
L
V
Cat
Felis silvestris
Mouse
Mus musculus
O08529
700
79854
S250
D
I
T
S
A
A
D
S
E
A
V
T
Y
Q
K
Rat
Rattus norvegicus
Q07009
700
79901
S250
D
I
T
S
A
A
D
S
E
A
V
T
Y
Q
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513498
700
79649
T250
D
I
T
S
A
S
E
T
E
A
V
T
F
Q
K
Chicken
Gallus gallus
Q92178
700
79210
T250
D
I
T
S
A
A
E
T
E
A
V
T
S
Q
K
Frog
Xenopus laevis
NP_001083713
699
79286
T250
D
I
T
S
A
A
E
T
E
A
I
T
F
Q
K
Zebra Danio
Brachydanio rerio
NP_001017807
700
78575
S250
D
I
T
S
S
S
D
S
E
A
I
T
S
Q
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VT65
925
103795
L458
L
E
P
D
P
H
V
L
E
A
E
T
P
Q
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
61.9
99.5
85
N.A.
94
93.8
N.A.
86.5
81.2
72.2
69.1
N.A.
36.4
N.A.
N.A.
N.A.
Protein Similarity:
100
79.2
99.8
89.5
N.A.
97.2
97.4
N.A.
95.2
90.8
88
83.1
N.A.
51.4
N.A.
N.A.
N.A.
P-Site Identity:
100
66.6
93.3
0
N.A.
86.6
86.6
N.A.
73.3
73.3
86.6
80
N.A.
26.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
80
100
26.6
N.A.
100
100
N.A.
100
93.3
100
93.3
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
64
55
0
10
0
91
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
82
0
0
10
10
0
55
0
0
0
0
0
0
0
0
% D
% Glu:
0
10
0
0
0
0
37
0
91
0
10
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
0
37
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
82
0
0
0
0
0
0
10
0
46
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
82
% K
% Leu:
10
0
0
0
0
10
0
10
0
0
0
0
0
10
0
% L
% Met:
0
0
10
0
0
0
0
10
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
10
0
10
0
0
0
0
0
0
0
10
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
10
0
82
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
10
10
82
10
28
0
46
0
0
0
0
19
0
0
% S
% Thr:
10
0
73
0
0
0
0
28
0
10
0
91
0
0
0
% T
% Val:
0
0
0
0
10
0
10
0
0
0
37
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
28
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _