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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CAPN2 All Species: 33.03
Human Site: T347 Identified Species: 72.67
UniProt: P17655 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P17655 NP_001139540.1 700 80009 T347 I C N L T P D T L T S D T Y K
Chimpanzee Pan troglodytes XP_001169048 714 81876 A357 I C N L T P D A L K S R T I R
Rhesus Macaque Macaca mulatta XP_001098172 700 80008 T347 I C N L T P D T L T S D T Y K
Dog Lupus familis XP_537240 677 77624 T324 I C N L T P D T L T S E S Y K
Cat Felis silvestris
Mouse Mus musculus O08529 700 79854 T347 I C N L T P D T L T C D S Y K
Rat Rattus norvegicus Q07009 700 79901 T347 I C N L T P D T L T C D S Y K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513498 700 79649 T347 I C N L T P D T L T S E T F K
Chicken Gallus gallus Q92178 700 79210 T347 I C N L T P D T L A S D R Y K
Frog Xenopus laevis NP_001083713 699 79286 T347 I C N L T P D T L A S D K Y S
Zebra Danio Brachydanio rerio NP_001017807 700 78575 A347 I C N L T P D A L T D E S V N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VT65 925 103795 S561 I C N L S P D S L T E D Q Q H
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 61.9 99.5 85 N.A. 94 93.8 N.A. 86.5 81.2 72.2 69.1 N.A. 36.4 N.A. N.A. N.A.
Protein Similarity: 100 79.2 99.8 89.5 N.A. 97.2 97.4 N.A. 95.2 90.8 88 83.1 N.A. 51.4 N.A. N.A. N.A.
P-Site Identity: 100 66.6 100 86.6 N.A. 86.6 86.6 N.A. 86.6 86.6 80 60 N.A. 60 N.A. N.A. N.A.
P-Site Similarity: 100 73.3 100 100 N.A. 93.3 93.3 N.A. 100 86.6 80 73.3 N.A. 73.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 19 0 19 0 0 0 0 0 % A
% Cys: 0 100 0 0 0 0 0 0 0 0 19 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 100 0 0 0 10 64 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 10 28 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % H
% Ile: 100 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 10 0 0 10 0 64 % K
% Leu: 0 0 0 100 0 0 0 0 100 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 100 0 0 0 0 0 0 0 0 0 0 0 10 % N
% Pro: 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 10 10 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 10 10 0 10 % R
% Ser: 0 0 0 0 10 0 0 10 0 0 64 0 37 0 10 % S
% Thr: 0 0 0 0 91 0 0 73 0 73 0 0 37 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 64 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _