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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AMD1
All Species:
46.36
Human Site:
S251
Identified Species:
63.75
UniProt:
P17707
Number Species:
16
Phosphosite Substitution
Charge Score:
0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P17707
NP_001625.2
334
38340
S251
I
T
P
E
P
E
F
S
Y
V
S
F
E
T
N
Chimpanzee
Pan troglodytes
XP_001155753
298
34239
F219
P
E
F
S
Y
V
S
F
E
T
N
L
S
Q
T
Rhesus Macaque
Macaca mulatta
XP_001086562
333
37991
S250
I
T
P
E
P
E
F
S
Y
V
S
F
E
T
N
Dog
Lupus familis
XP_539081
336
38588
S253
I
T
P
E
P
E
F
S
Y
V
S
F
E
T
N
Cat
Felis silvestris
Mouse
Mus musculus
P31154
334
38254
S251
I
T
P
E
P
E
F
S
Y
V
S
F
E
T
N
Rat
Rattus norvegicus
P17708
333
38119
S251
I
T
P
E
P
E
F
S
Y
V
S
F
E
T
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514093
331
38011
S248
I
T
P
E
P
E
F
S
Y
V
S
F
E
T
N
Chicken
Gallus gallus
NP_001012587
341
39453
S258
I
T
P
E
P
E
F
S
Y
V
S
F
E
T
N
Frog
Xenopus laevis
P79888
335
38801
S253
I
T
P
E
P
D
F
S
Y
V
S
F
E
T
N
Zebra Danio
Brachydanio rerio
NP_001155073
334
38713
S251
I
T
P
E
P
E
F
S
Y
V
S
F
E
T
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91931
347
39798
S259
I
T
P
E
N
Q
F
S
Y
V
S
F
E
T
N
Honey Bee
Apis mellifera
XP_624115
271
31123
E191
E
F
S
Y
V
S
F
E
S
N
I
P
E
A
S
Nematode Worm
Caenorhab. elegans
O02655
368
42125
A267
I
H
V
T
P
E
K
A
F
S
F
A
S
F
E
Sea Urchin
Strong. purpuratus
XP_001187713
329
37876
S249
A
S
M
E
D
Y
S
S
L
V
D
R
I
L
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
O24575
400
43497
Y265
T
P
E
D
G
F
S
Y
A
S
Y
E
V
M
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q96286
366
40385
Y255
T
P
E
D
G
F
S
Y
A
S
F
E
A
V
G
Baker's Yeast
Sacchar. cerevisiae
P21182
396
46214
S309
V
T
P
E
K
G
W
S
Y
A
S
F
E
S
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.2
90.7
97.9
N.A.
98.1
97.3
N.A.
84.1
87.6
83.5
81.1
N.A.
48.9
39.5
39.4
44.3
Protein Similarity:
100
89.2
91.6
99.4
N.A.
99.6
99
N.A.
88
92
90.1
91.3
N.A.
65.4
55
53.5
62.2
P-Site Identity:
100
0
100
100
N.A.
100
100
N.A.
100
100
93.3
100
N.A.
86.6
13.3
20
20
P-Site Similarity:
100
6.6
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
93.3
20
33.3
33.3
Percent
Protein Identity:
N.A.
29.7
N.A.
33.3
30.8
N.A.
Protein Similarity:
N.A.
44.7
N.A.
50.5
51.5
N.A.
P-Site Identity:
N.A.
0
N.A.
0
60
N.A.
P-Site Similarity:
N.A.
6.6
N.A.
6.6
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
0
0
0
0
0
0
6
12
6
0
6
6
6
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
12
6
6
0
0
0
0
6
0
0
0
0
% D
% Glu:
6
6
12
71
0
53
0
6
6
0
0
12
71
0
6
% E
% Phe:
0
6
6
0
0
12
65
6
6
0
12
65
0
6
0
% F
% Gly:
0
0
0
0
12
6
0
0
0
0
0
0
0
0
12
% G
% His:
0
6
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
65
0
0
0
0
0
0
0
0
0
6
0
6
0
0
% I
% Lys:
0
0
0
0
6
0
6
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
6
0
0
6
0
6
0
% L
% Met:
0
0
6
0
0
0
0
0
0
0
0
0
0
6
0
% M
% Asn:
0
0
0
0
6
0
0
0
0
6
6
0
0
0
65
% N
% Pro:
6
12
65
0
59
0
0
0
0
0
0
6
0
0
0
% P
% Gln:
0
0
0
0
0
6
0
0
0
0
0
0
0
6
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
6
0
0
0
% R
% Ser:
0
6
6
6
0
6
24
71
6
18
65
0
12
6
12
% S
% Thr:
12
65
0
6
0
0
0
0
0
6
0
0
0
59
6
% T
% Val:
6
0
6
0
6
6
0
0
0
65
0
0
6
6
0
% V
% Trp:
0
0
0
0
0
0
6
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
6
6
6
0
12
65
0
6
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _