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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AMD1
All Species:
42.42
Human Site:
S53
Identified Species:
58.33
UniProt:
P17707
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P17707
NP_001625.2
334
38340
S53
D
V
Q
C
S
I
I
S
V
T
K
T
D
K
Q
Chimpanzee
Pan troglodytes
XP_001155753
298
34239
S29
Q
P
D
A
N
Q
G
S
G
D
L
R
T
I
P
Rhesus Macaque
Macaca mulatta
XP_001086562
333
37991
S52
D
V
Q
C
S
I
I
S
V
T
K
T
D
K
Q
Dog
Lupus familis
XP_539081
336
38588
S55
D
V
Q
C
S
I
I
S
V
T
K
T
D
K
Q
Cat
Felis silvestris
Mouse
Mus musculus
P31154
334
38254
S53
D
V
Q
C
S
I
I
S
V
T
K
T
D
K
Q
Rat
Rattus norvegicus
P17708
333
38119
S53
D
V
Q
C
S
I
I
S
V
T
K
T
D
K
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514093
331
38011
V51
V
H
C
L
I
I
S
V
T
K
T
D
K
Q
E
Chicken
Gallus gallus
NP_001012587
341
39453
S60
N
V
H
C
L
I
I
S
V
T
K
T
D
K
Q
Frog
Xenopus laevis
P79888
335
38801
S55
N
V
H
C
L
I
I
S
V
T
K
T
D
K
Q
Zebra Danio
Brachydanio rerio
NP_001155073
334
38713
S53
N
V
H
C
L
I
I
S
V
T
K
T
D
K
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91931
347
39798
S51
N
V
N
C
Q
I
I
S
T
S
K
N
D
I
I
Honey Bee
Apis mellifera
XP_624115
271
31123
Nematode Worm
Caenorhab. elegans
O02655
368
42125
H68
I
A
R
C
K
I
L
H
S
K
H
N
E
S
I
Sea Urchin
Strong. purpuratus
XP_001187713
329
37876
S55
R
V
I
P
S
E
S
S
L
F
I
S
K
R
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
O24575
400
43497
S63
L
A
R
C
T
I
V
S
E
L
S
N
K
D
F
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q96286
366
40385
S54
P
A
A
C
T
I
V
S
S
L
S
N
D
Q
L
Baker's Yeast
Sacchar. cerevisiae
P21182
396
46214
S73
L
V
K
C
E
V
L
S
M
K
K
T
K
E
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.2
90.7
97.9
N.A.
98.1
97.3
N.A.
84.1
87.6
83.5
81.1
N.A.
48.9
39.5
39.4
44.3
Protein Similarity:
100
89.2
91.6
99.4
N.A.
99.6
99
N.A.
88
92
90.1
91.3
N.A.
65.4
55
53.5
62.2
P-Site Identity:
100
6.6
100
100
N.A.
100
100
N.A.
6.6
80
80
80
N.A.
46.6
0
13.3
20
P-Site Similarity:
100
13.3
100
100
N.A.
100
100
N.A.
20
86.6
86.6
86.6
N.A.
60
0
33.3
46.6
Percent
Protein Identity:
N.A.
29.7
N.A.
33.3
30.8
N.A.
Protein Similarity:
N.A.
44.7
N.A.
50.5
51.5
N.A.
P-Site Identity:
N.A.
20
N.A.
26.6
33.3
N.A.
P-Site Similarity:
N.A.
40
N.A.
46.6
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
18
6
6
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
6
77
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
30
0
6
0
0
0
0
0
0
6
0
6
59
6
0
% D
% Glu:
0
0
0
0
6
6
0
0
6
0
0
0
6
6
6
% E
% Phe:
0
0
0
0
0
0
0
0
0
6
0
0
0
0
6
% F
% Gly:
0
0
0
0
0
0
6
0
6
0
0
0
0
0
0
% G
% His:
0
6
18
0
0
0
0
6
0
0
6
0
0
0
0
% H
% Ile:
6
0
6
0
6
77
53
0
0
0
6
0
0
12
12
% I
% Lys:
0
0
6
0
6
0
0
0
0
18
59
0
24
48
0
% K
% Leu:
12
0
0
6
18
0
12
0
6
12
6
0
0
0
12
% L
% Met:
0
0
0
0
0
0
0
0
6
0
0
0
0
0
0
% M
% Asn:
24
0
6
0
6
0
0
0
0
0
0
24
0
0
0
% N
% Pro:
6
6
0
6
0
0
0
0
0
0
0
0
0
0
6
% P
% Gln:
6
0
30
0
6
6
0
0
0
0
0
0
0
12
48
% Q
% Arg:
6
0
12
0
0
0
0
0
0
0
0
6
0
6
6
% R
% Ser:
0
0
0
0
36
0
12
83
12
6
12
6
0
6
0
% S
% Thr:
0
0
0
0
12
0
0
0
12
48
6
53
6
0
0
% T
% Val:
6
65
0
0
0
6
12
6
48
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _