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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AMD1 All Species: 53.33
Human Site: S68 Identified Species: 73.33
UniProt: P17707 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P17707 NP_001625.2 334 38340 S68 E A Y V L S E S S M F V S K R
Chimpanzee Pan troglodytes XP_001155753 298 34239 L44 R S E W D I L L K D V Q C S I
Rhesus Macaque Macaca mulatta XP_001086562 333 37991 S67 E A Y V L S E S S M F V S K R
Dog Lupus familis XP_539081 336 38588 S70 E A Y V L S E S S M F V S K R
Cat Felis silvestris
Mouse Mus musculus P31154 334 38254 S68 E A Y V L S E S S M F V S K R
Rat Rattus norvegicus P17708 333 38119 S68 E A Y V L S E S S M F V S K R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514093 331 38011 S66 A Y V L S E S S M F V S K R R
Chicken Gallus gallus NP_001012587 341 39453 S75 E A Y V L S E S S M F V S K R
Frog Xenopus laevis P79888 335 38801 S70 E A Y V L S E S S M F V S K R
Zebra Danio Brachydanio rerio NP_001155073 334 38713 S68 E A Y I L S E S S M F V S K R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91931 347 39798 S66 D A F V L S E S S M F V S K R
Honey Bee Apis mellifera XP_624115 271 31123 C16 R R L I L K T C G T T T P L Q
Nematode Worm Caenorhab. elegans O02655 368 42125 S83 D S Y V L S E S S L F I S D N
Sea Urchin Strong. purpuratus XP_001187713 329 37876 T70 L I L K T C G T T T V L A S L
Poplar Tree Populus trichocarpa
Maize Zea mays O24575 400 43497 S78 D S Y V L S E S S L F I Y P L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q96286 366 40385 S69 D S Y V L S E S S F F V Y P Y
Baker's Yeast Sacchar. cerevisiae P21182 396 46214 S88 D A F L L S E S S L F V F D H
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89.2 90.7 97.9 N.A. 98.1 97.3 N.A. 84.1 87.6 83.5 81.1 N.A. 48.9 39.5 39.4 44.3
Protein Similarity: 100 89.2 91.6 99.4 N.A. 99.6 99 N.A. 88 92 90.1 91.3 N.A. 65.4 55 53.5 62.2
P-Site Identity: 100 0 100 100 N.A. 100 100 N.A. 13.3 100 100 93.3 N.A. 86.6 6.6 60 0
P-Site Similarity: 100 6.6 100 100 N.A. 100 100 N.A. 26.6 100 100 100 N.A. 100 20 86.6 26.6
Percent
Protein Identity: N.A. 29.7 N.A. 33.3 30.8 N.A.
Protein Similarity: N.A. 44.7 N.A. 50.5 51.5 N.A.
P-Site Identity: N.A. 53.3 N.A. 60 53.3 N.A.
P-Site Similarity: N.A. 80 N.A. 73.3 80 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 59 0 0 0 0 0 0 0 0 0 0 6 0 0 % A
% Cys: 0 0 0 0 0 6 0 6 0 0 0 0 6 0 0 % C
% Asp: 30 0 0 0 6 0 0 0 0 6 0 0 0 12 0 % D
% Glu: 48 0 6 0 0 6 77 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 12 0 0 0 0 0 0 12 77 0 6 0 0 % F
% Gly: 0 0 0 0 0 0 6 0 6 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 % H
% Ile: 0 6 0 12 0 6 0 0 0 0 0 12 0 0 6 % I
% Lys: 0 0 0 6 0 6 0 0 6 0 0 0 6 53 0 % K
% Leu: 6 0 12 12 83 0 6 6 0 18 0 6 0 6 12 % L
% Met: 0 0 0 0 0 0 0 0 6 53 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 6 12 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 6 0 0 6 % Q
% Arg: 12 6 0 0 0 0 0 0 0 0 0 0 0 6 59 % R
% Ser: 0 24 0 0 6 77 6 83 77 0 0 6 59 12 0 % S
% Thr: 0 0 0 0 6 0 6 6 6 12 6 6 0 0 0 % T
% Val: 0 0 6 65 0 0 0 0 0 0 18 65 0 0 0 % V
% Trp: 0 0 0 6 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 6 65 0 0 0 0 0 0 0 0 0 12 0 6 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _