KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AMD1
All Species:
46.36
Human Site:
S73
Identified Species:
63.75
UniProt:
P17707
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P17707
NP_001625.2
334
38340
S73
S
E
S
S
M
F
V
S
K
R
R
F
I
L
K
Chimpanzee
Pan troglodytes
XP_001155753
298
34239
C49
I
L
L
K
D
V
Q
C
S
I
I
S
V
T
K
Rhesus Macaque
Macaca mulatta
XP_001086562
333
37991
S72
S
E
S
S
M
F
V
S
K
R
R
F
I
L
K
Dog
Lupus familis
XP_539081
336
38588
S75
S
E
S
S
M
F
V
S
K
R
R
F
I
L
K
Cat
Felis silvestris
Mouse
Mus musculus
P31154
334
38254
S73
S
E
S
S
M
F
V
S
K
R
R
F
I
L
K
Rat
Rattus norvegicus
P17708
333
38119
S73
S
E
S
S
M
F
V
S
K
R
R
F
I
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514093
331
38011
K71
E
S
S
M
F
V
S
K
R
R
F
I
L
K
T
Chicken
Gallus gallus
NP_001012587
341
39453
S80
S
E
S
S
M
F
V
S
K
R
R
F
I
L
K
Frog
Xenopus laevis
P79888
335
38801
S75
S
E
S
S
M
F
V
S
K
R
R
F
I
L
K
Zebra Danio
Brachydanio rerio
NP_001155073
334
38713
S73
S
E
S
S
M
F
V
S
K
R
R
F
I
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91931
347
39798
S71
S
E
S
S
M
F
V
S
K
R
R
W
I
L
K
Honey Bee
Apis mellifera
XP_624115
271
31123
P21
K
T
C
G
T
T
T
P
L
Q
C
L
E
P
L
Nematode Worm
Caenorhab. elegans
O02655
368
42125
S88
S
E
S
S
L
F
I
S
D
N
R
V
I
L
K
Sea Urchin
Strong. purpuratus
XP_001187713
329
37876
A75
C
G
T
T
T
V
L
A
S
L
D
S
L
L
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
O24575
400
43497
Y83
S
E
S
S
L
F
I
Y
P
L
K
I
V
I
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q96286
366
40385
Y74
S
E
S
S
F
F
V
Y
P
Y
K
V
I
I
K
Baker's Yeast
Sacchar. cerevisiae
P21182
396
46214
F93
S
E
S
S
L
F
V
F
D
H
K
L
T
M
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.2
90.7
97.9
N.A.
98.1
97.3
N.A.
84.1
87.6
83.5
81.1
N.A.
48.9
39.5
39.4
44.3
Protein Similarity:
100
89.2
91.6
99.4
N.A.
99.6
99
N.A.
88
92
90.1
91.3
N.A.
65.4
55
53.5
62.2
P-Site Identity:
100
6.6
100
100
N.A.
100
100
N.A.
13.3
100
100
100
N.A.
93.3
0
66.6
6.6
P-Site Similarity:
100
13.3
100
100
N.A.
100
100
N.A.
26.6
100
100
100
N.A.
100
6.6
80
40
Percent
Protein Identity:
N.A.
29.7
N.A.
33.3
30.8
N.A.
Protein Similarity:
N.A.
44.7
N.A.
50.5
51.5
N.A.
P-Site Identity:
N.A.
40
N.A.
53.3
46.6
N.A.
P-Site Similarity:
N.A.
73.3
N.A.
66.6
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
6
0
0
0
0
0
0
6
% A
% Cys:
6
0
6
0
0
0
0
6
0
0
6
0
0
0
0
% C
% Asp:
0
0
0
0
6
0
0
0
12
0
6
0
0
0
0
% D
% Glu:
6
77
0
0
0
0
0
0
0
0
0
0
6
0
0
% E
% Phe:
0
0
0
0
12
77
0
6
0
0
6
48
0
0
0
% F
% Gly:
0
6
0
6
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
6
0
0
0
0
0
% H
% Ile:
6
0
0
0
0
0
12
0
0
6
6
12
65
12
0
% I
% Lys:
6
0
0
6
0
0
0
6
53
0
18
0
0
6
83
% K
% Leu:
0
6
6
0
18
0
6
0
6
12
0
12
12
65
6
% L
% Met:
0
0
0
6
53
0
0
0
0
0
0
0
0
6
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
6
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
6
12
0
0
0
0
6
0
% P
% Gln:
0
0
0
0
0
0
6
0
0
6
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
6
59
59
0
0
0
0
% R
% Ser:
77
6
83
77
0
0
6
59
12
0
0
12
0
0
0
% S
% Thr:
0
6
6
6
12
6
6
0
0
0
0
0
6
6
6
% T
% Val:
0
0
0
0
0
18
65
0
0
0
0
12
12
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
6
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
12
0
6
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _