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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AMD1
All Species:
38.48
Human Site:
Y264
Identified Species:
52.92
UniProt:
P17707
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P17707
NP_001625.2
334
38340
Y264
T
N
L
S
Q
T
S
Y
D
D
L
I
R
K
V
Chimpanzee
Pan troglodytes
XP_001155753
298
34239
I232
Q
T
S
Y
D
D
L
I
R
K
V
V
E
V
F
Rhesus Macaque
Macaca mulatta
XP_001086562
333
37991
Y263
T
N
L
S
Q
T
S
Y
D
D
L
I
R
K
V
Dog
Lupus familis
XP_539081
336
38588
Y266
T
N
L
S
Q
T
S
Y
D
D
L
I
R
K
V
Cat
Felis silvestris
Mouse
Mus musculus
P31154
334
38254
Y264
T
N
L
S
Q
T
S
Y
D
D
L
I
R
K
V
Rat
Rattus norvegicus
P17708
333
38119
Y264
T
N
L
S
Q
T
S
Y
D
D
L
I
R
K
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514093
331
38011
Y261
T
N
I
G
Q
T
S
Y
D
D
L
I
R
K
V
Chicken
Gallus gallus
NP_001012587
341
39453
Y271
T
N
I
S
Q
T
S
Y
D
D
L
I
R
K
V
Frog
Xenopus laevis
P79888
335
38801
Y266
T
N
V
S
L
T
T
Y
D
D
L
I
S
K
V
Zebra Danio
Brachydanio rerio
NP_001155073
334
38713
Y264
T
N
L
S
Q
T
S
Y
D
E
L
I
C
R
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91931
347
39798
Y272
T
N
V
A
L
S
N
Y
R
K
L
I
N
Q
V
Honey Bee
Apis mellifera
XP_624115
271
31123
R204
A
S
Y
E
E
I
I
R
R
V
L
N
T
F
K
Nematode Worm
Caenorhab. elegans
O02655
368
42125
V280
F
E
T
N
Q
D
L
V
C
L
Y
S
Q
T
R
Sea Urchin
Strong. purpuratus
XP_001187713
329
37876
K262
L
S
T
F
R
P
G
K
F
V
M
T
L
F
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
O24575
400
43497
L278
M
G
L
D
A
T
A
L
S
Y
G
D
L
V
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q96286
366
40385
L268
V
G
Y
D
F
N
T
L
D
L
S
Q
L
V
T
Baker's Yeast
Sacchar. cerevisiae
P21182
396
46214
I322
S
N
I
P
V
F
D
I
S
Q
G
K
Q
D
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.2
90.7
97.9
N.A.
98.1
97.3
N.A.
84.1
87.6
83.5
81.1
N.A.
48.9
39.5
39.4
44.3
Protein Similarity:
100
89.2
91.6
99.4
N.A.
99.6
99
N.A.
88
92
90.1
91.3
N.A.
65.4
55
53.5
62.2
P-Site Identity:
100
0
100
100
N.A.
100
100
N.A.
86.6
93.3
73.3
80
N.A.
40
6.6
6.6
0
P-Site Similarity:
100
13.3
100
100
N.A.
100
100
N.A.
93.3
100
86.6
93.3
N.A.
73.3
20
20
20
Percent
Protein Identity:
N.A.
29.7
N.A.
33.3
30.8
N.A.
Protein Similarity:
N.A.
44.7
N.A.
50.5
51.5
N.A.
P-Site Identity:
N.A.
13.3
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
20
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
0
0
6
6
0
6
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
6
0
0
0
6
0
0
% C
% Asp:
0
0
0
12
6
12
6
0
59
48
0
6
0
6
0
% D
% Glu:
0
6
0
6
6
0
0
0
0
6
0
0
6
0
0
% E
% Phe:
6
0
0
6
6
6
0
0
6
0
0
0
0
12
6
% F
% Gly:
0
12
0
6
0
0
6
0
0
0
12
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
18
0
0
6
6
12
0
0
0
59
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
6
0
12
0
6
0
48
12
% K
% Leu:
6
0
42
0
12
0
12
12
0
12
65
0
18
0
0
% L
% Met:
6
0
0
0
0
0
0
0
0
0
6
0
0
0
0
% M
% Asn:
0
65
0
6
0
6
6
0
0
0
0
6
6
0
6
% N
% Pro:
0
0
0
6
0
6
0
0
0
0
0
0
0
0
0
% P
% Gln:
6
0
0
0
53
0
0
0
0
6
0
6
12
6
0
% Q
% Arg:
0
0
0
0
6
0
0
6
18
0
0
0
42
6
6
% R
% Ser:
6
12
6
48
0
6
48
0
12
0
6
6
6
0
0
% S
% Thr:
59
6
12
0
0
59
12
0
0
0
0
6
6
6
12
% T
% Val:
6
0
12
0
6
0
0
6
0
12
6
6
0
18
59
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
12
6
0
0
0
59
0
6
6
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _