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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHRNB2
All Species:
13.64
Human Site:
S416
Identified Species:
25
UniProt:
P17787
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P17787
NP_000739.1
502
57019
S416
P
V
A
G
P
G
R
S
G
E
P
C
G
C
G
Chimpanzee
Pan troglodytes
Q5IS52
529
59755
T435
H
V
A
P
S
V
G
T
L
C
S
H
G
H
L
Rhesus Macaque
Macaca mulatta
XP_001114439
502
57033
S416
P
V
A
G
P
G
R
S
G
E
P
C
G
C
G
Dog
Lupus familis
XP_547565
478
54433
G394
G
S
A
R
G
G
V
G
T
D
G
C
G
L
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9ERK7
501
57094
S415
A
A
A
G
L
G
R
S
M
G
P
C
S
C
G
Rat
Rattus norvegicus
P12390
500
56890
S414
T
A
A
G
P
G
R
S
V
G
P
C
S
C
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513131
979
112159
S407
Q
R
D
F
R
L
R
S
S
K
K
Y
Q
P
E
Chicken
Gallus gallus
P09484
491
56014
P405
R
Q
G
Q
G
P
D
P
P
A
P
C
G
C
G
Frog
Xenopus laevis
NP_001088299
499
57252
Q413
V
N
G
F
R
D
R
Q
G
K
V
R
Q
C
L
Zebra Danio
Brachydanio rerio
XP_690400
542
60482
N425
G
G
S
T
D
G
L
N
G
I
R
E
G
G
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P09478
567
64001
N446
L
F
S
P
S
G
L
N
G
D
I
S
P
G
C
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N587
502
57373
N417
E
L
L
S
P
G
L
N
S
N
R
E
E
S
S
Sea Urchin
Strong. purpuratus
XP_786790
570
65253
Y475
M
S
K
G
G
G
R
Y
S
K
E
F
K
Q
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
47.2
99.1
90
N.A.
94
93.4
N.A.
35.1
83
84
75.6
N.A.
44
N.A.
45.4
46.3
Protein Similarity:
100
60.2
99.4
92.6
N.A.
95.4
94.6
N.A.
43.3
87.4
89
81.7
N.A.
59.9
N.A.
63.5
61.2
P-Site Identity:
100
20
100
26.6
N.A.
60
66.6
N.A.
13.3
33.3
20
20
N.A.
13.3
N.A.
13.3
20
P-Site Similarity:
100
26.6
100
33.3
N.A.
60
66.6
N.A.
20
33.3
26.6
33.3
N.A.
33.3
N.A.
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
16
47
0
0
0
0
0
0
8
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
47
0
47
8
% C
% Asp:
0
0
8
0
8
8
8
0
0
16
0
0
0
0
0
% D
% Glu:
8
0
0
0
0
0
0
0
0
16
8
16
8
0
8
% E
% Phe:
0
8
0
16
0
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
16
8
16
39
24
70
8
8
39
16
8
0
47
16
39
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% I
% Lys:
0
0
8
0
0
0
0
0
0
24
8
0
8
0
0
% K
% Leu:
8
8
8
0
8
8
24
0
8
0
0
0
0
8
16
% L
% Met:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
24
0
8
0
0
0
0
0
% N
% Pro:
16
0
0
16
31
8
0
8
8
0
39
0
8
8
0
% P
% Gln:
8
8
0
8
0
0
0
8
0
0
0
0
16
8
0
% Q
% Arg:
8
8
0
8
16
0
54
0
0
0
16
8
0
0
16
% R
% Ser:
0
16
16
8
16
0
0
39
24
0
8
8
16
8
8
% S
% Thr:
8
0
0
8
0
0
0
8
8
0
0
0
0
0
0
% T
% Val:
8
24
0
0
0
8
8
0
8
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _