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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHRNB2
All Species:
14.55
Human Site:
S494
Identified Species:
26.67
UniProt:
P17787
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P17787
NP_000739.1
502
57019
S494
T
T
T
T
F
L
H
S
D
H
S
A
P
S
S
Chimpanzee
Pan troglodytes
Q5IS52
529
59755
P522
G
T
I
G
L
F
L
P
P
F
L
A
G
M
I
Rhesus Macaque
Macaca mulatta
XP_001114439
502
57033
S494
T
T
T
T
F
L
H
S
D
H
S
A
P
S
S
Dog
Lupus familis
XP_547565
478
54433
T470
S
A
A
T
F
L
H
T
D
H
S
A
P
S
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9ERK7
501
57094
S493
T
A
T
T
F
L
H
S
D
H
S
A
P
S
S
Rat
Rattus norvegicus
P12390
500
56890
P492
T
A
T
T
F
L
H
P
D
H
S
A
P
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513131
979
112159
T485
L
M
P
R
Y
L
E
T
L
K
K
R
S
H
D
Chicken
Gallus gallus
P09484
491
56014
L483
A
T
N
S
L
L
Q
L
G
Q
G
T
P
T
S
Frog
Xenopus laevis
NP_001088299
499
57252
T489
F
Q
N
Y
T
T
N
T
F
L
Q
I
N
H
A
Zebra Danio
Brachydanio rerio
XP_690400
542
60482
A534
P
L
F
Q
N
Y
T
A
K
T
I
T
H
T
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P09478
567
64001
F556
S
K
I
A
K
K
K
F
E
L
L
K
M
G
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N587
502
57373
A489
F
G
T
V
V
I
I
A
R
A
P
S
I
Y
D
Sea Urchin
Strong. purpuratus
XP_786790
570
65253
R549
P
V
V
T
Q
I
E
R
D
E
A
A
M
T
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
47.2
99.1
90
N.A.
94
93.4
N.A.
35.1
83
84
75.6
N.A.
44
N.A.
45.4
46.3
Protein Similarity:
100
60.2
99.4
92.6
N.A.
95.4
94.6
N.A.
43.3
87.4
89
81.7
N.A.
59.9
N.A.
63.5
61.2
P-Site Identity:
100
13.3
100
66.6
N.A.
93.3
86.6
N.A.
6.6
26.6
0
0
N.A.
6.6
N.A.
6.6
20
P-Site Similarity:
100
13.3
100
86.6
N.A.
93.3
86.6
N.A.
20
40
20
13.3
N.A.
20
N.A.
26.6
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
24
8
8
0
0
0
16
0
8
8
54
0
0
24
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
47
0
0
0
0
0
16
% D
% Glu:
0
0
0
0
0
0
16
0
8
8
0
0
0
0
0
% E
% Phe:
16
0
8
0
39
8
0
8
8
8
0
0
0
0
0
% F
% Gly:
8
8
0
8
0
0
0
0
8
0
8
0
8
8
0
% G
% His:
0
0
0
0
0
0
39
0
0
39
0
0
8
16
0
% H
% Ile:
0
0
16
0
0
16
8
0
0
0
8
8
8
0
8
% I
% Lys:
0
8
0
0
8
8
8
0
8
8
8
8
0
0
0
% K
% Leu:
8
8
0
0
16
54
8
8
8
16
16
0
0
0
0
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
16
8
0
% M
% Asn:
0
0
16
0
8
0
8
0
0
0
0
0
8
0
0
% N
% Pro:
16
0
8
0
0
0
0
16
8
0
8
0
47
0
8
% P
% Gln:
0
8
0
8
8
0
8
0
0
8
8
0
0
0
0
% Q
% Arg:
0
0
0
8
0
0
0
8
8
0
0
8
0
0
0
% R
% Ser:
16
0
0
8
0
0
0
24
0
0
39
8
8
39
47
% S
% Thr:
31
31
39
47
8
8
8
24
0
8
0
16
0
24
0
% T
% Val:
0
8
8
8
8
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
8
8
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _