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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHRNB2
All Species:
18.18
Human Site:
T487
Identified Species:
33.33
UniProt:
P17787
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P17787
NP_000739.1
502
57019
T487
Q
P
L
F
Q
N
Y
T
T
T
T
F
L
H
S
Chimpanzee
Pan troglodytes
Q5IS52
529
59755
G515
F
I
I
V
C
F
L
G
T
I
G
L
F
L
P
Rhesus Macaque
Macaca mulatta
XP_001114439
502
57033
T487
Q
P
L
F
Q
N
Y
T
T
T
T
F
L
H
S
Dog
Lupus familis
XP_547565
478
54433
S463
Q
P
L
F
Q
N
Y
S
A
A
T
F
L
H
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9ERK7
501
57094
T486
Q
P
L
F
Q
N
Y
T
A
T
T
F
L
H
S
Rat
Rattus norvegicus
P12390
500
56890
T485
Q
P
L
F
Q
N
Y
T
A
T
T
F
L
H
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513131
979
112159
L478
P
P
L
F
Q
N
I
L
M
P
R
Y
L
E
T
Chicken
Gallus gallus
P09484
491
56014
A476
Q
P
L
F
Q
N
Y
A
T
N
S
L
L
Q
L
Frog
Xenopus laevis
NP_001088299
499
57252
F482
G
M
F
L
Q
P
L
F
Q
N
Y
T
T
N
T
Zebra Danio
Brachydanio rerio
XP_690400
542
60482
P527
T
I
G
M
F
L
Q
P
L
F
Q
N
Y
T
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P09478
567
64001
S549
Q
P
I
D
I
L
Y
S
K
I
A
K
K
K
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N587
502
57373
F482
T
F
T
F
A
C
A
F
G
T
V
V
I
I
A
Sea Urchin
Strong. purpuratus
XP_786790
570
65253
P542
S
A
P
L
I
F
E
P
V
V
T
Q
I
E
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
47.2
99.1
90
N.A.
94
93.4
N.A.
35.1
83
84
75.6
N.A.
44
N.A.
45.4
46.3
Protein Similarity:
100
60.2
99.4
92.6
N.A.
95.4
94.6
N.A.
43.3
87.4
89
81.7
N.A.
59.9
N.A.
63.5
61.2
P-Site Identity:
100
6.6
100
73.3
N.A.
93.3
86.6
N.A.
40
60
6.6
0
N.A.
20
N.A.
13.3
6.6
P-Site Similarity:
100
13.3
100
86.6
N.A.
93.3
86.6
N.A.
53.3
66.6
20
6.6
N.A.
33.3
N.A.
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
0
8
8
24
8
8
0
0
0
16
% A
% Cys:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
8
0
0
0
0
0
0
16
0
% E
% Phe:
8
8
8
62
8
16
0
16
0
8
0
39
8
0
8
% F
% Gly:
8
0
8
0
0
0
0
8
8
0
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
39
0
% H
% Ile:
0
16
16
0
16
0
8
0
0
16
0
0
16
8
0
% I
% Lys:
0
0
0
0
0
0
0
0
8
0
0
8
8
8
0
% K
% Leu:
0
0
54
16
0
16
16
8
8
0
0
16
54
8
8
% L
% Met:
0
8
0
8
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
54
0
0
0
16
0
8
0
8
0
% N
% Pro:
8
62
8
0
0
8
0
16
0
8
0
0
0
0
16
% P
% Gln:
54
0
0
0
62
0
8
0
8
0
8
8
0
8
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
8
% R
% Ser:
8
0
0
0
0
0
0
16
0
0
8
0
0
0
24
% S
% Thr:
16
0
8
0
0
0
0
31
31
39
47
8
8
8
24
% T
% Val:
0
0
0
8
0
0
0
0
8
8
8
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
54
0
0
0
8
8
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _