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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTPS
All Species:
34.85
Human Site:
S562
Identified Species:
58.97
UniProt:
P17812
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P17812
NP_001896.2
591
66690
S562
L
Q
K
G
C
R
L
S
P
R
D
T
Y
S
D
Chimpanzee
Pan troglodytes
XP_524681
591
66712
S562
L
Q
K
G
C
R
L
S
P
R
D
T
Y
S
D
Rhesus Macaque
Macaca mulatta
XP_001084608
591
66746
S562
L
Q
K
G
C
R
L
S
P
R
D
T
Y
S
D
Dog
Lupus familis
XP_537968
586
65447
F525
P
Y
F
V
G
V
Q
F
H
P
E
F
S
S
R
Cat
Felis silvestris
Mouse
Mus musculus
P70698
591
66664
S562
L
Q
K
G
C
R
L
S
P
R
D
T
Y
S
D
Rat
Rattus norvegicus
Q5U2N0
586
65655
S537
S
S
R
P
M
K
P
S
P
P
Y
L
G
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506472
591
66548
S562
L
Q
K
G
C
R
L
S
P
R
D
T
Y
S
D
Chicken
Gallus gallus
Q5F3Z1
586
66050
F525
P
Y
F
V
G
V
Q
F
H
P
E
F
S
S
R
Frog
Xenopus laevis
Q5XHA8
591
66854
S562
I
E
R
G
C
R
L
S
P
R
D
T
Y
S
D
Zebra Danio
Brachydanio rerio
Q6PEI7
591
66577
S562
L
Q
K
G
C
R
L
S
P
R
D
A
Y
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUL1
627
69429
S562
I
Q
R
G
C
R
L
S
P
R
Q
L
S
D
A
Honey Bee
Apis mellifera
XP_624223
604
67926
S563
L
V
K
G
C
K
L
S
P
Q
A
I
S
D
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P28274
579
64692
Y534
P
Y
Y
I
A
T
Q
Y
H
P
E
Y
T
S
K
Red Bread Mold
Neurospora crassa
Q7RZV2
568
63157
L535
L
D
P
S
R
P
F
L
G
F
V
A
A
A
I
Conservation
Percent
Protein Identity:
100
99.6
99.4
75.3
N.A.
97.8
74.1
N.A.
94.7
76.9
89.1
86.6
N.A.
63.3
65.5
N.A.
N.A.
Protein Similarity:
100
99.8
99.8
85.2
N.A.
98.3
85.1
N.A.
97.1
87.6
95.5
92.8
N.A.
77
79.1
N.A.
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
100
13.3
N.A.
100
6.6
80
93.3
N.A.
53.3
46.6
N.A.
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
100
26.6
N.A.
100
13.3
100
93.3
N.A.
66.6
66.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
57.1
51.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
72.5
68.1
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
0
0
8
15
8
8
8
% A
% Cys:
0
0
0
0
65
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
0
0
0
50
0
0
15
50
% D
% Glu:
0
8
0
0
0
0
0
0
0
0
22
0
0
0
0
% E
% Phe:
0
0
15
0
0
0
8
15
0
8
0
15
0
0
0
% F
% Gly:
0
0
0
65
15
0
0
0
8
0
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
22
0
0
0
0
0
0
% H
% Ile:
15
0
0
8
0
0
0
0
0
0
0
8
0
0
8
% I
% Lys:
0
0
50
0
0
15
0
0
0
0
0
0
0
0
8
% K
% Leu:
58
0
0
0
0
0
65
8
0
0
0
15
0
8
8
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
22
0
8
8
0
8
8
0
72
29
0
0
0
0
0
% P
% Gln:
0
50
0
0
0
0
22
0
0
8
8
0
0
0
0
% Q
% Arg:
0
0
22
0
8
58
0
0
0
58
0
0
0
0
15
% R
% Ser:
8
8
0
8
0
0
0
72
0
0
0
0
29
72
0
% S
% Thr:
0
0
0
0
0
8
0
0
0
0
0
43
8
0
0
% T
% Val:
0
8
0
15
0
15
0
0
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
22
8
0
0
0
0
8
0
0
8
8
50
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _