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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTPS
All Species:
20.61
Human Site:
S578
Identified Species:
34.87
UniProt:
P17812
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P17812
NP_001896.2
591
66690
S578
S
G
S
S
S
P
D
S
E
I
T
E
L
K
F
Chimpanzee
Pan troglodytes
XP_524681
591
66712
S578
S
G
S
S
S
P
D
S
E
I
T
E
L
K
F
Rhesus Macaque
Macaca mulatta
XP_001084608
591
66746
S578
S
G
S
S
S
P
D
S
E
I
T
E
L
K
F
Dog
Lupus familis
XP_537968
586
65447
L541
L
K
P
S
P
P
Y
L
G
L
L
L
A
A
T
Cat
Felis silvestris
Mouse
Mus musculus
P70698
591
66664
S578
S
G
S
S
S
P
D
S
E
I
T
E
L
K
F
Rat
Rattus norvegicus
Q5U2N0
586
65655
T553
A
A
T
G
T
L
N
T
H
L
Q
Q
M
S
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506472
591
66548
S578
S
G
S
S
S
P
D
S
E
I
T
E
L
K
F
Chicken
Gallus gallus
Q5F3Z1
586
66050
L541
M
K
P
S
P
P
Y
L
G
L
L
L
A
A
T
Frog
Xenopus laevis
Q5XHA8
591
66854
A578
S
E
N
S
S
P
D
A
E
I
A
E
L
K
L
Zebra Danio
Brachydanio rerio
Q6PEI7
591
66577
L578
S
G
S
S
S
P
D
L
E
I
A
D
L
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUL1
627
69429
V578
S
D
E
E
D
S
V
V
G
L
A
G
A
T
K
Honey Bee
Apis mellifera
XP_624223
604
67926
D579
S
D
N
E
C
L
V
D
S
I
A
K
Q
Q
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P28274
579
64692
L550
L
D
P
S
K
P
F
L
G
L
V
A
A
S
A
Red Bread Mold
Neurospora crassa
Q7RZV2
568
63157
E551
C
L
D
Q
I
T
K
E
I
L
Q
D
A
G
F
Conservation
Percent
Protein Identity:
100
99.6
99.4
75.3
N.A.
97.8
74.1
N.A.
94.7
76.9
89.1
86.6
N.A.
63.3
65.5
N.A.
N.A.
Protein Similarity:
100
99.8
99.8
85.2
N.A.
98.3
85.1
N.A.
97.1
87.6
95.5
92.8
N.A.
77
79.1
N.A.
N.A.
P-Site Identity:
100
100
100
13.3
N.A.
100
0
N.A.
100
13.3
66.6
73.3
N.A.
6.6
13.3
N.A.
N.A.
P-Site Similarity:
100
100
100
20
N.A.
100
53.3
N.A.
100
20
80
80
N.A.
13.3
33.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
57.1
51.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
72.5
68.1
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
0
0
8
0
0
29
8
36
15
8
% A
% Cys:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
22
8
0
8
0
50
8
0
0
0
15
0
0
0
% D
% Glu:
0
8
8
15
0
0
0
8
50
0
0
43
0
0
0
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
43
% F
% Gly:
0
43
0
8
0
0
0
0
29
0
0
8
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
0
8
58
0
0
0
0
0
% I
% Lys:
0
15
0
0
8
0
8
0
0
0
0
8
0
50
15
% K
% Leu:
15
8
0
0
0
15
0
29
0
43
15
15
50
0
15
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
15
0
0
0
8
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
22
0
15
72
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
0
0
0
0
0
0
15
8
8
8
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
65
0
43
72
50
8
0
36
8
0
0
0
0
15
0
% S
% Thr:
0
0
8
0
8
8
0
8
0
0
36
0
0
8
22
% T
% Val:
0
0
0
0
0
0
15
8
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
15
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _