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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTPS
All Species:
34.85
Human Site:
T459
Identified Species:
58.97
UniProt:
P17812
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P17812
NP_001896.2
591
66690
T459
K
R
R
T
L
F
Q
T
K
N
S
V
M
R
K
Chimpanzee
Pan troglodytes
XP_524681
591
66712
T459
K
R
R
T
L
F
Q
T
K
N
S
V
M
R
K
Rhesus Macaque
Macaca mulatta
XP_001084608
591
66746
T459
K
R
R
T
L
F
Q
T
K
N
S
V
M
R
K
Dog
Lupus familis
XP_537968
586
65447
T459
I
R
R
T
V
F
K
T
E
N
S
I
L
R
K
Cat
Felis silvestris
Mouse
Mus musculus
P70698
591
66664
T459
K
R
R
T
L
F
Q
T
K
N
S
V
M
R
K
Rat
Rattus norvegicus
Q5U2N0
586
65655
T459
L
R
R
T
V
F
T
T
E
N
S
I
L
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506472
591
66548
T459
K
R
R
T
L
F
Q
T
K
T
S
I
M
R
K
Chicken
Gallus gallus
Q5F3Z1
586
66050
T459
K
R
R
T
V
F
K
T
Q
N
S
I
L
R
K
Frog
Xenopus laevis
Q5XHA8
591
66854
S459
K
R
R
T
I
F
H
S
Q
N
S
I
M
K
K
Zebra Danio
Brachydanio rerio
Q6PEI7
591
66577
N459
K
R
R
T
I
F
K
N
K
S
S
I
L
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUL1
627
69429
D459
K
R
I
T
V
F
S
D
G
P
S
V
I
R
Q
Honey Bee
Apis mellifera
XP_624223
604
67926
E460
K
R
Y
T
R
F
T
E
N
N
S
V
I
K
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P28274
579
64692
N466
L
R
P
T
F
F
Q
N
E
T
E
W
S
Q
I
Red Bread Mold
Neurospora crassa
Q7RZV2
568
63157
P451
T
R
S
T
H
F
Q
P
G
S
E
F
S
K
L
Conservation
Percent
Protein Identity:
100
99.6
99.4
75.3
N.A.
97.8
74.1
N.A.
94.7
76.9
89.1
86.6
N.A.
63.3
65.5
N.A.
N.A.
Protein Similarity:
100
99.8
99.8
85.2
N.A.
98.3
85.1
N.A.
97.1
87.6
95.5
92.8
N.A.
77
79.1
N.A.
N.A.
P-Site Identity:
100
100
100
60
N.A.
100
53.3
N.A.
86.6
66.6
60
60
N.A.
46.6
46.6
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
100
86.6
N.A.
93.3
100
93.3
93.3
N.A.
66.6
66.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
57.1
51.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
72.5
68.1
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
8
22
0
15
0
0
0
0
% E
% Phe:
0
0
0
0
8
100
0
0
0
0
0
8
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
15
0
0
0
0
0
0
% G
% His:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
8
0
15
0
0
0
0
0
0
43
15
0
8
% I
% Lys:
72
0
0
0
0
0
22
0
43
0
0
0
0
29
72
% K
% Leu:
15
0
0
0
36
0
0
0
0
0
0
0
29
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
43
0
0
% M
% Asn:
0
0
0
0
0
0
0
15
8
65
0
0
0
0
0
% N
% Pro:
0
0
8
0
0
0
0
8
0
8
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
50
0
15
0
0
0
0
8
15
% Q
% Arg:
0
100
72
0
8
0
0
0
0
0
0
0
0
65
0
% R
% Ser:
0
0
8
0
0
0
8
8
0
15
86
0
15
0
0
% S
% Thr:
8
0
0
100
0
0
15
58
0
15
0
0
0
0
0
% T
% Val:
0
0
0
0
29
0
0
0
0
0
0
43
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _