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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CTPS All Species: 50
Human Site: Y53 Identified Species: 84.62
UniProt: P17812 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P17812 NP_001896.2 591 66690 Y53 D A G T F S P Y E H G E V F V
Chimpanzee Pan troglodytes XP_524681 591 66712 Y53 D A G T F S P Y E H G E V F V
Rhesus Macaque Macaca mulatta XP_001084608 591 66746 Y53 D A G T F S P Y E H G E V F V
Dog Lupus familis XP_537968 586 65447 Y53 D A G T F S P Y E H G E V F V
Cat Felis silvestris
Mouse Mus musculus P70698 591 66664 Y53 D A G T F S P Y E H G E V F V
Rat Rattus norvegicus Q5U2N0 586 65655 Y53 D A G T F S P Y E H G E V F V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506472 591 66548 Y53 D A G T F S P Y E H G E V F V
Chicken Gallus gallus Q5F3Z1 586 66050 Y53 D A G T F S P Y E H G E V F V
Frog Xenopus laevis Q5XHA8 591 66854 Y53 D A G T F S P Y E H G E V F V
Zebra Danio Brachydanio rerio Q6PEI7 591 66577 Y53 D A G T F S P Y E H G E V F V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VUL1 627 69429 Y53 D A G T F S P Y E H G E V Y V
Honey Bee Apis mellifera XP_624223 604 67926 Y53 D A G T F S P Y E H G E V Y V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P28274 579 64692 L53 D A G T M S P L E H G E C F V
Red Bread Mold Neurospora crassa Q7RZV2 568 63157 G53 E C F V L H D G G E T D L D L
Conservation
Percent
Protein Identity: 100 99.6 99.4 75.3 N.A. 97.8 74.1 N.A. 94.7 76.9 89.1 86.6 N.A. 63.3 65.5 N.A. N.A.
Protein Similarity: 100 99.8 99.8 85.2 N.A. 98.3 85.1 N.A. 97.1 87.6 95.5 92.8 N.A. 77 79.1 N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 93.3 93.3 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 100 100 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 57.1 51.7
Protein Similarity: N.A. N.A. N.A. N.A. 72.5 68.1
P-Site Identity: N.A. N.A. N.A. N.A. 80 0
P-Site Similarity: N.A. N.A. N.A. N.A. 80 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 93 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 8 0 0 0 0 0 0 0 0 0 0 8 0 0 % C
% Asp: 93 0 0 0 0 0 8 0 0 0 0 8 0 8 0 % D
% Glu: 8 0 0 0 0 0 0 0 93 8 0 93 0 0 0 % E
% Phe: 0 0 8 0 86 0 0 0 0 0 0 0 0 79 0 % F
% Gly: 0 0 93 0 0 0 0 8 8 0 93 0 0 0 0 % G
% His: 0 0 0 0 0 8 0 0 0 93 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 8 0 0 8 0 0 0 0 8 0 8 % L
% Met: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 93 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 93 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 93 0 0 0 0 0 0 8 0 0 0 0 % T
% Val: 0 0 0 8 0 0 0 0 0 0 0 0 86 0 93 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 86 0 0 0 0 0 15 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _