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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PFKL
All Species:
42.42
Human Site:
T82
Identified Species:
77.78
UniProt:
P17858
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P17858
NP_002617.3
780
85018
T82
N
I
I
Q
L
G
G
T
I
I
G
S
A
R
C
Chimpanzee
Pan troglodytes
XP_001150233
780
84936
T82
N
I
I
Q
L
G
G
T
I
I
G
S
A
R
C
Rhesus Macaque
Macaca mulatta
XP_001096244
851
93251
T153
M
M
L
Q
L
G
G
T
V
I
G
S
A
R
C
Dog
Lupus familis
XP_544922
751
82459
T82
N
L
V
Q
R
G
I
T
N
L
C
V
I
G
G
Cat
Felis silvestris
Mouse
Mus musculus
P12382
780
85282
T82
N
I
I
Q
L
G
G
T
I
I
G
S
A
R
C
Rat
Rattus norvegicus
P30835
780
85320
T82
N
I
I
Q
L
G
G
T
I
I
G
S
A
R
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514123
751
82475
T82
N
L
V
Q
H
G
I
T
N
L
C
V
I
G
G
Chicken
Gallus gallus
XP_001232621
780
85127
T82
N
I
I
Q
L
G
G
T
V
I
G
S
A
R
C
Frog
Xenopus laevis
NP_001091319
786
86623
T83
S
I
L
Q
V
G
G
T
V
I
G
S
A
R
C
Zebra Danio
Brachydanio rerio
XP_698635
780
84600
T82
N
I
I
Q
L
G
G
T
V
I
G
S
A
R
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P52034
788
86630
T84
S
I
I
H
R
G
G
T
I
I
G
S
A
R
C
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q27483
756
83282
G78
H
L
G
G
S
M
I
G
T
S
R
C
D
E
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P16862
959
104599
T264
G
W
S
A
E
G
G
T
N
I
G
T
A
R
C
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
63.8
90.1
N.A.
94
94.2
N.A.
86.6
86.7
68.4
77.5
N.A.
55.5
N.A.
40.1
N.A.
Protein Similarity:
100
99.6
77.3
93
N.A.
97.1
97.3
N.A.
91.9
93.8
83.7
89.6
N.A.
73
N.A.
58.2
N.A.
P-Site Identity:
100
100
73.3
26.6
N.A.
100
100
N.A.
26.6
93.3
73.3
93.3
N.A.
80
N.A.
0
N.A.
P-Site Similarity:
100
100
93.3
46.6
N.A.
100
100
N.A.
46.6
100
100
100
N.A.
86.6
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
36.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
0
0
0
0
0
77
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
16
8
0
0
77
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% D
% Glu:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
8
0
8
8
0
93
77
8
0
0
77
0
0
16
16
% G
% His:
8
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
62
54
0
0
0
24
0
39
77
0
0
16
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
24
16
0
54
0
0
0
0
16
0
0
0
0
0
% L
% Met:
8
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
62
0
0
0
0
0
0
0
24
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
77
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
16
0
0
0
0
0
8
0
0
77
0
% R
% Ser:
16
0
8
0
8
0
0
0
0
8
0
70
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
93
8
0
0
8
0
0
0
% T
% Val:
0
0
16
0
8
0
0
0
31
0
0
16
0
0
0
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _