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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XBP1
All Species:
15.15
Human Site:
S216
Identified Species:
33.33
UniProt:
P17861
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P17861
NP_001073007.1
261
28695
S216
T
T
W
T
Q
S
C
S
S
N
A
L
P
Q
S
Chimpanzee
Pan troglodytes
XP_515053
262
28747
S217
T
T
W
T
Q
S
C
S
S
N
A
L
P
Q
S
Rhesus Macaque
Macaca mulatta
XP_001103490
261
28546
S216
T
T
W
T
Q
S
C
S
S
N
A
L
P
Q
S
Dog
Lupus familis
XP_854633
385
41353
S332
T
S
D
L
L
S
S
S
H
C
L
K
P
S
S
Cat
Felis silvestris
Mouse
Mus musculus
O35426
267
29601
F211
T
S
W
T
L
S
C
F
S
N
V
L
P
Q
S
Rat
Rattus norvegicus
Q9R1S4
267
29647
F211
T
S
W
T
L
S
C
F
S
N
V
L
P
Q
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080523
396
43419
F280
V
K
M
E
E
A
S
F
S
P
T
C
E
D
D
Zebra Danio
Brachydanio rerio
NP_571949
263
29172
S218
T
S
L
T
P
S
S
S
S
R
Q
T
F
L
K
Tiger Blowfish
Takifugu rubipres
NP_001033032
261
28776
S216
C
F
W
A
F
W
T
S
L
T
Q
S
C
S
S
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392383
439
49522
T283
P
V
S
S
T
A
S
T
S
Y
T
T
S
T
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790957
276
31233
Q224
C
S
A
S
S
T
R
Q
P
S
A
E
P
F
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.4
45.9
N.A.
79.7
81.6
N.A.
N.A.
N.A.
35
56.6
57.4
N.A.
21.4
N.A.
30.8
Protein Similarity:
100
99.6
99.2
52.2
N.A.
82.4
84.6
N.A.
N.A.
N.A.
45.4
68
69.7
N.A.
35.5
N.A.
43.1
P-Site Identity:
100
100
100
33.3
N.A.
73.3
73.3
N.A.
N.A.
N.A.
6.6
33.3
20
N.A.
13.3
N.A.
13.3
P-Site Similarity:
100
100
100
40
N.A.
80
80
N.A.
N.A.
N.A.
20
40
20
N.A.
33.3
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
10
0
19
0
0
0
0
37
0
0
0
0
% A
% Cys:
19
0
0
0
0
0
46
0
0
10
0
10
10
0
0
% C
% Asp:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
10
% D
% Glu:
0
0
0
10
10
0
0
0
0
0
0
10
10
0
0
% E
% Phe:
0
10
0
0
10
0
0
28
0
0
0
0
10
10
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
0
0
0
0
0
0
0
0
10
0
0
10
% K
% Leu:
0
0
10
10
28
0
0
0
10
0
10
46
0
10
0
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
46
0
0
0
0
0
% N
% Pro:
10
0
0
0
10
0
0
0
10
10
0
0
64
0
0
% P
% Gln:
0
0
0
0
28
0
0
10
0
0
19
0
0
46
0
% Q
% Arg:
0
0
0
0
0
0
10
0
0
10
0
0
0
0
0
% R
% Ser:
0
46
10
19
10
64
37
55
73
10
0
10
10
19
73
% S
% Thr:
64
28
0
55
10
10
10
10
0
10
19
19
0
10
0
% T
% Val:
10
10
0
0
0
0
0
0
0
0
19
0
0
0
10
% V
% Trp:
0
0
55
0
0
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _