Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: XBP1 All Species: 20
Human Site: S223 Identified Species: 44
UniProt: P17861 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P17861 NP_001073007.1 261 28695 S223 S S N A L P Q S L P A W R S S
Chimpanzee Pan troglodytes XP_515053 262 28747 S224 S S N A L P Q S L P A W R S S
Rhesus Macaque Macaca mulatta XP_001103490 261 28546 S223 S S N A L P Q S L P A W R S S
Dog Lupus familis XP_854633 385 41353 S339 S H C L K P S S C L L D A Y S
Cat Felis silvestris
Mouse Mus musculus O35426 267 29601 S218 F S N V L P Q S L L V W R N S
Rat Rattus norvegicus Q9R1S4 267 29647 S218 F S N V L P Q S L L I W R N S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001080523 396 43419 D287 F S P T C E D D L T C V K Q E
Zebra Danio Brachydanio rerio NP_571949 263 29172 K225 S S R Q T F L K H R S L S R S
Tiger Blowfish Takifugu rubipres NP_001033032 261 28776 S223 S L T Q S C S S D L V S R S R
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392383 439 49522 S290 T S Y T T S T S V P M S I K S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790957 276 31233 V231 Q P S A E P F V F S A Q K D R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 98.4 45.9 N.A. 79.7 81.6 N.A. N.A. N.A. 35 56.6 57.4 N.A. 21.4 N.A. 30.8
Protein Similarity: 100 99.6 99.2 52.2 N.A. 82.4 84.6 N.A. N.A. N.A. 45.4 68 69.7 N.A. 35.5 N.A. 43.1
P-Site Identity: 100 100 100 26.6 N.A. 66.6 66.6 N.A. N.A. N.A. 13.3 20 26.6 N.A. 26.6 N.A. 20
P-Site Similarity: 100 100 100 26.6 N.A. 73.3 73.3 N.A. N.A. N.A. 20 26.6 26.6 N.A. 40 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 37 0 0 0 0 0 0 37 0 10 0 0 % A
% Cys: 0 0 10 0 10 10 0 0 10 0 10 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 10 10 10 0 0 10 0 10 0 % D
% Glu: 0 0 0 0 10 10 0 0 0 0 0 0 0 0 10 % E
% Phe: 28 0 0 0 0 10 10 0 10 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 10 0 0 0 0 0 0 10 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 10 0 10 0 0 % I
% Lys: 0 0 0 0 10 0 0 10 0 0 0 0 19 10 0 % K
% Leu: 0 10 0 10 46 0 10 0 55 37 10 10 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % M
% Asn: 0 0 46 0 0 0 0 0 0 0 0 0 0 19 0 % N
% Pro: 0 10 10 0 0 64 0 0 0 37 0 0 0 0 0 % P
% Gln: 10 0 0 19 0 0 46 0 0 0 0 10 0 10 0 % Q
% Arg: 0 0 10 0 0 0 0 0 0 10 0 0 55 10 19 % R
% Ser: 55 73 10 0 10 10 19 73 0 10 10 19 10 37 73 % S
% Thr: 10 0 10 19 19 0 10 0 0 10 0 0 0 0 0 % T
% Val: 0 0 0 19 0 0 0 10 10 0 19 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 46 0 0 0 % W
% Tyr: 0 0 10 0 0 0 0 0 0 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _