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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XBP1
All Species:
24.11
Human Site:
S255
Identified Species:
53.05
UniProt:
P17861
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P17861
NP_001073007.1
261
28695
S255
Q
W
G
R
H
Q
P
S
W
K
P
L
M
N
_
Chimpanzee
Pan troglodytes
XP_515053
262
28747
S256
Q
W
G
R
H
Q
P
S
W
K
P
L
M
N
_
Rhesus Macaque
Macaca mulatta
XP_001103490
261
28546
S255
Q
W
G
R
H
Q
P
S
W
K
P
L
M
N
_
Dog
Lupus familis
XP_854633
385
41353
E371
L
G
V
D
H
S
W
E
D
T
F
A
N
E
L
Cat
Felis silvestris
Mouse
Mus musculus
O35426
267
29601
S250
Q
W
G
P
H
Q
P
S
W
K
P
L
M
N
S
Rat
Rattus norvegicus
Q9R1S4
267
29647
S250
Q
W
G
P
H
Q
P
S
W
K
P
L
M
N
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080523
396
43419
K319
C
S
E
N
N
L
E
K
S
S
N
I
L
D
T
Zebra Danio
Brachydanio rerio
NP_571949
263
29172
S257
L
W
G
P
H
Q
L
S
W
K
P
L
M
N
_
Tiger Blowfish
Takifugu rubipres
NP_001033032
261
28776
S255
L
W
G
P
H
Q
L
S
W
R
P
L
M
N
_
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392383
439
49522
N322
G
T
Y
D
E
A
T
N
S
V
M
I
I
Y
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790957
276
31233
W263
S
K
R
N
A
G
D
W
W
G
P
Q
Q
Q
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.4
45.9
N.A.
79.7
81.6
N.A.
N.A.
N.A.
35
56.6
57.4
N.A.
21.4
N.A.
30.8
Protein Similarity:
100
99.6
99.2
52.2
N.A.
82.4
84.6
N.A.
N.A.
N.A.
45.4
68
69.7
N.A.
35.5
N.A.
43.1
P-Site Identity:
100
100
100
6.6
N.A.
86.6
86.6
N.A.
N.A.
N.A.
0
78.5
71.4
N.A.
0
N.A.
13.3
P-Site Similarity:
100
100
100
6.6
N.A.
86.6
86.6
N.A.
N.A.
N.A.
26.6
78.5
78.5
N.A.
20
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
10
0
0
0
0
0
10
0
0
0
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
19
0
0
10
0
10
0
0
0
0
10
0
% D
% Glu:
0
0
10
0
10
0
10
10
0
0
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
10
10
64
0
0
10
0
0
0
10
0
0
0
0
0
% G
% His:
0
0
0
0
73
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
19
10
0
0
% I
% Lys:
0
10
0
0
0
0
0
10
0
55
0
0
0
0
0
% K
% Leu:
28
0
0
0
0
10
19
0
0
0
0
64
10
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
64
0
0
% M
% Asn:
0
0
0
19
10
0
0
10
0
0
10
0
10
64
0
% N
% Pro:
0
0
0
37
0
0
46
0
0
0
73
0
0
0
10
% P
% Gln:
46
0
0
0
0
64
0
0
0
0
0
10
10
10
0
% Q
% Arg:
0
0
10
28
0
0
0
0
0
10
0
0
0
0
0
% R
% Ser:
10
10
0
0
0
10
0
64
19
10
0
0
0
0
28
% S
% Thr:
0
10
0
0
0
0
10
0
0
10
0
0
0
0
10
% T
% Val:
0
0
10
0
0
0
0
0
0
10
0
0
0
0
0
% V
% Trp:
0
64
0
0
0
0
10
10
73
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
46
% _