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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XBP1
All Species:
20.3
Human Site:
Y241
Identified Species:
44.67
UniProt:
P17861
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P17861
NP_001073007.1
261
28695
Y241
T
Q
K
D
P
V
P
Y
Q
P
P
F
L
C
Q
Chimpanzee
Pan troglodytes
XP_515053
262
28747
Y242
T
Q
K
D
P
V
P
Y
Q
P
P
F
L
C
Q
Rhesus Macaque
Macaca mulatta
XP_001103490
261
28546
Y241
T
Q
K
D
P
V
P
Y
Q
P
P
F
L
C
Q
Dog
Lupus familis
XP_854633
385
41353
F357
Y
E
G
S
P
S
P
F
S
D
M
S
S
L
L
Cat
Felis silvestris
Mouse
Mus musculus
O35426
267
29601
Y236
T
Q
K
D
L
V
P
Y
Q
P
P
F
L
C
Q
Rat
Rattus norvegicus
Q9R1S4
267
29647
Y236
T
Q
K
D
L
V
P
Y
Q
P
P
F
L
C
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080523
396
43419
G305
D
D
L
V
P
I
L
G
M
Q
S
F
L
P
C
Zebra Danio
Brachydanio rerio
NP_571949
263
29172
Y243
W
G
V
Q
E
S
K
Y
L
P
P
H
L
Q
L
Tiger Blowfish
Takifugu rubipres
NP_001033032
261
28776
Y241
W
S
E
G
G
T
Q
Y
L
P
P
H
L
R
L
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392383
439
49522
H308
I
K
Q
E
D
M
T
H
D
L
D
T
I
Y
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790957
276
31233
L249
R
E
E
E
P
L
C
L
V
T
R
K
T
K
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.4
45.9
N.A.
79.7
81.6
N.A.
N.A.
N.A.
35
56.6
57.4
N.A.
21.4
N.A.
30.8
Protein Similarity:
100
99.6
99.2
52.2
N.A.
82.4
84.6
N.A.
N.A.
N.A.
45.4
68
69.7
N.A.
35.5
N.A.
43.1
P-Site Identity:
100
100
100
13.3
N.A.
93.3
93.3
N.A.
N.A.
N.A.
20
26.6
26.6
N.A.
0
N.A.
6.6
P-Site Similarity:
100
100
100
26.6
N.A.
93.3
93.3
N.A.
N.A.
N.A.
26.6
26.6
33.3
N.A.
40
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
0
0
0
46
10
% C
% Asp:
10
10
0
46
10
0
0
0
10
10
10
0
0
0
0
% D
% Glu:
0
19
19
19
10
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
55
0
0
0
% F
% Gly:
0
10
10
10
10
0
0
10
0
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
10
0
0
0
19
0
0
0
% H
% Ile:
10
0
0
0
0
10
0
0
0
0
0
0
10
0
0
% I
% Lys:
0
10
46
0
0
0
10
0
0
0
0
10
0
10
0
% K
% Leu:
0
0
10
0
19
10
10
10
19
10
0
0
73
10
28
% L
% Met:
0
0
0
0
0
10
0
0
10
0
10
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
55
0
55
0
0
64
64
0
0
10
0
% P
% Gln:
0
46
10
10
0
0
10
0
46
10
0
0
0
10
46
% Q
% Arg:
10
0
0
0
0
0
0
0
0
0
10
0
0
10
0
% R
% Ser:
0
10
0
10
0
19
0
0
10
0
10
10
10
0
10
% S
% Thr:
46
0
0
0
0
10
10
0
0
10
0
10
10
0
0
% T
% Val:
0
0
10
10
0
46
0
0
10
0
0
0
0
0
0
% V
% Trp:
19
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
64
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _