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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GM2A
All Species:
20.3
Human Site:
S35
Identified Species:
63.81
UniProt:
P17900
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P17900
NP_000396.2
193
20838
S35
P
S
Q
L
S
S
F
S
W
D
N
C
D
E
G
Chimpanzee
Pan troglodytes
XP_527083
193
20758
S35
P
S
Q
L
S
S
F
S
W
D
N
C
D
E
G
Rhesus Macaque
Macaca mulatta
XP_001109570
190
20546
S32
L
K
K
L
G
S
F
S
W
D
N
C
D
E
G
Dog
Lupus familis
XP_536462
196
21559
F38
P
P
K
S
G
S
F
F
W
N
N
C
D
R
A
Cat
Felis silvestris
Mouse
Mus musculus
Q60648
193
20806
S35
L
S
Q
L
G
G
F
S
W
D
N
C
D
E
G
Rat
Rattus norvegicus
NP_758838
199
21475
S41
P
S
Q
L
G
G
F
S
W
D
N
C
D
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509067
205
22362
S48
I
S
L
V
S
G
F
S
W
E
N
C
D
D
G
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795968
185
20068
Y34
T
P
Q
K
P
E
R
Y
F
S
P
V
D
V
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
90.6
57.6
N.A.
70.9
68.8
N.A.
52.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
29.5
Protein Similarity:
100
99.4
95.3
76
N.A.
83.4
80.4
N.A.
66.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
43
P-Site Identity:
100
100
73.3
46.6
N.A.
80
86.6
N.A.
60
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
80
60
N.A.
80
86.6
N.A.
80
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
13
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
88
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
63
0
0
100
13
0
% D
% Glu:
0
0
0
0
0
13
0
0
0
13
0
0
0
63
0
% E
% Phe:
0
0
0
0
0
0
88
13
13
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
50
38
0
0
0
0
0
0
0
0
75
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
13
25
13
0
0
0
0
0
0
0
0
0
0
13
% K
% Leu:
25
0
13
63
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
13
88
0
0
0
0
% N
% Pro:
50
25
0
0
13
0
0
0
0
0
13
0
0
0
0
% P
% Gln:
0
0
63
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
13
0
0
0
0
0
0
13
0
% R
% Ser:
0
63
0
13
38
50
0
75
0
13
0
0
0
0
0
% S
% Thr:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
13
0
0
0
0
0
0
0
13
0
13
0
% V
% Trp:
0
0
0
0
0
0
0
0
88
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _