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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LGALS3 All Species: 21.21
Human Site: S237 Identified Species: 46.67
UniProt: P17931 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P17931 NP_002297.2 250 26152 S237 E I S K L G I S G D I D L T S
Chimpanzee Pan troglodytes XP_001148424 357 37768 S344 E I S K L A I S G D I D L T S
Rhesus Macaque Macaca mulatta XP_001085890 255 27015 S242 E I S Q L G I S G D I D L T N
Dog Lupus familis XP_853675 287 29487 S274 E I S K L G I S G D I D L T S
Cat Felis silvestris
Mouse Mus musculus P16110 264 27496 S251 E I S Q L G I S G D I T L T S
Rat Rattus norvegicus P08699 262 27183 I249 E I S Q L G I I G D I T L T S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507412 266 27642 S253 Q I T G L A I S G D I T L T S
Chicken Gallus gallus Q5ZHQ2 171 19026 I159 T L S A I D T I K I N G D L Q
Frog Xenopus laevis Q6DDR8 171 19215 I159 S L S A I N T I K I N G D L Q
Zebra Danio Brachydanio rerio Q6DGJ1 139 16307 K127 L Q V V N D V K I S S L E I T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P36573 279 31791 Q266 P H D I A G L Q I S G D I E L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 68.6 91.7 76.6 N.A. 80.3 80.5 N.A. 68.8 21.2 24.7 23.6 N.A. N.A. N.A. 24.7 N.A.
Protein Similarity: 100 68.9 93.3 81.1 N.A. 86.3 86.2 N.A. 75.5 35.2 37.5 35.5 N.A. N.A. N.A. 40.1 N.A.
P-Site Identity: 100 93.3 86.6 100 N.A. 86.6 80 N.A. 66.6 6.6 6.6 0 N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: 100 93.3 100 100 N.A. 93.3 86.6 N.A. 80 20 20 13.3 N.A. N.A. N.A. 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 19 10 19 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 0 19 0 0 0 64 0 46 19 0 0 % D
% Glu: 55 0 0 0 0 0 0 0 0 0 0 0 10 10 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 10 0 55 0 0 64 0 10 19 0 0 0 % G
% His: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 64 0 10 19 0 64 28 19 19 64 0 10 10 0 % I
% Lys: 0 0 0 28 0 0 0 10 19 0 0 0 0 0 0 % K
% Leu: 10 19 0 0 64 0 10 0 0 0 0 10 64 19 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 10 10 0 0 0 0 19 0 0 0 10 % N
% Pro: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 10 10 0 28 0 0 0 10 0 0 0 0 0 0 19 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 10 0 73 0 0 0 0 55 0 19 10 0 0 0 55 % S
% Thr: 10 0 10 0 0 0 19 0 0 0 0 28 0 64 10 % T
% Val: 0 0 10 10 0 0 10 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _