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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IGFBP3
All Species:
7.27
Human Site:
S155
Identified Species:
17.78
UniProt:
P17936
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P17936
NP_000589.2
291
31674
S155
S
V
E
S
P
S
V
S
S
T
H
R
V
S
D
Chimpanzee
Pan troglodytes
XP_511475
258
27929
H123
S
D
K
D
E
G
D
H
P
N
N
S
F
S
P
Rhesus Macaque
Macaca mulatta
XP_001085359
291
31575
S155
S
V
E
S
P
S
V
S
S
T
H
R
V
S
D
Dog
Lupus familis
XP_548740
563
59524
P427
A
G
G
A
Q
A
L
P
G
T
H
R
V
P
D
Cat
Felis silvestris
Mouse
Mus musculus
P47878
291
31701
P155
S
V
E
S
Q
V
V
P
S
T
H
R
V
T
D
Rat
Rattus norvegicus
P15473
292
31661
P156
S
V
E
S
Q
V
V
P
S
T
H
R
V
T
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507772
210
23181
N75
L
E
T
Q
A
I
P
N
A
P
R
V
L
D
S
Chicken
Gallus gallus
P49705
311
33520
S161
G
G
M
M
S
G
A
S
S
R
K
P
L
K
T
Frog
Xenopus laevis
Q90WV8
265
29976
T127
E
D
P
T
T
S
E
T
E
D
I
Y
Q
S
K
Zebra Danio
Brachydanio rerio
Q9PTH3
276
30746
T141
V
P
P
I
R
K
P
T
K
D
S
P
W
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
35
98.6
42
N.A.
79.3
82.1
N.A.
52.9
32.7
40.8
31.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
47.7
99.6
45.6
N.A.
86.2
87.6
N.A.
58.7
45.9
56
45.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
100
33.3
N.A.
73.3
73.3
N.A.
0
13.3
13.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
100
60
N.A.
80
80
N.A.
20
20
26.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
10
10
10
10
0
10
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
20
0
10
0
0
10
0
0
20
0
0
0
10
50
% D
% Glu:
10
10
40
0
10
0
10
0
10
0
0
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
10
20
10
0
0
20
0
0
10
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
10
0
0
50
0
0
0
0
% H
% Ile:
0
0
0
10
0
10
0
0
0
0
10
0
0
0
0
% I
% Lys:
0
0
10
0
0
10
0
0
10
0
10
0
0
20
10
% K
% Leu:
10
0
0
0
0
0
10
0
0
0
0
0
20
0
0
% L
% Met:
0
0
10
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
10
10
0
0
0
0
% N
% Pro:
0
10
20
0
20
0
20
30
10
10
0
20
0
10
10
% P
% Gln:
0
0
0
10
30
0
0
0
0
0
0
0
10
0
0
% Q
% Arg:
0
0
0
0
10
0
0
0
0
10
10
50
0
0
0
% R
% Ser:
50
0
0
40
10
30
0
30
50
0
10
10
0
40
10
% S
% Thr:
0
0
10
10
10
0
0
20
0
50
0
0
0
20
10
% T
% Val:
10
40
0
0
0
20
40
0
0
0
0
10
50
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _