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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPI1
All Species:
9.09
Human Site:
S130
Identified Species:
25
UniProt:
P17947
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P17947
NP_003111.2
270
31083
S130
S
L
S
P
A
Q
P
S
S
D
E
E
E
G
E
Chimpanzee
Pan troglodytes
XP_508411
176
19620
F55
H
S
D
H
Y
W
D
F
H
P
H
H
V
H
S
Rhesus Macaque
Macaca mulatta
XP_001100894
183
20549
N62
E
F
E
S
F
A
E
N
N
F
T
E
L
Q
S
Dog
Lupus familis
XP_853990
270
31032
S130
S
L
S
P
A
Q
P
S
S
D
E
E
E
G
E
Cat
Felis silvestris
Mouse
Mus musculus
P17433
272
31331
Q131
T
L
S
P
A
H
Q
Q
S
S
D
E
E
E
G
Rat
Rattus norvegicus
Q6BDS1
271
31070
Q130
P
L
S
P
A
H
Q
Q
S
S
D
E
E
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_990354
256
29683
P129
D
I
E
R
Q
S
P
P
L
E
V
S
D
G
E
Frog
Xenopus laevis
NP_001079648
281
32067
S133
N
V
P
S
P
P
L
S
E
E
E
D
F
R
H
Zebra Danio
Brachydanio rerio
NP_932328
290
33927
S153
Q
P
S
P
L
Q
R
S
S
D
E
E
D
P
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58.1
60.7
96.6
N.A.
87.8
88.9
N.A.
N.A.
79.2
43
53
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
59.6
61.1
97.4
N.A.
91.9
92.9
N.A.
N.A.
89.2
57.2
65.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
6.6
100
N.A.
46.6
46.6
N.A.
N.A.
20
13.3
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
0
20
100
N.A.
60
53.3
N.A.
N.A.
40
40
60
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
45
12
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
0
12
0
0
0
12
0
0
34
23
12
23
0
0
% D
% Glu:
12
0
23
0
0
0
12
0
12
23
45
67
45
23
34
% E
% Phe:
0
12
0
0
12
0
0
12
0
12
0
0
12
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
34
23
% G
% His:
12
0
0
12
0
23
0
0
12
0
12
12
0
12
12
% H
% Ile:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
45
0
0
12
0
12
0
12
0
0
0
12
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
12
0
0
0
0
0
0
12
12
0
0
0
0
0
0
% N
% Pro:
12
12
12
56
12
12
34
12
0
12
0
0
0
12
0
% P
% Gln:
12
0
0
0
12
34
23
23
0
0
0
0
0
12
0
% Q
% Arg:
0
0
0
12
0
0
12
0
0
0
0
0
0
12
0
% R
% Ser:
23
12
56
23
0
12
0
45
56
23
0
12
0
0
34
% S
% Thr:
12
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% T
% Val:
0
12
0
0
0
0
0
0
0
0
12
0
12
0
0
% V
% Trp:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _