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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FLT1
All Species:
26.06
Human Site:
Y1124
Identified Species:
57.33
UniProt:
P17948
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P17948
NP_001153392.1
1338
150769
Y1124
M
R
M
R
A
P
E
Y
S
T
P
E
I
Y
Q
Chimpanzee
Pan troglodytes
XP_509605
1338
150659
Y1124
M
R
M
R
A
P
E
Y
S
T
P
E
I
Y
Q
Rhesus Macaque
Macaca mulatta
XP_001117928
1481
165481
Y1267
M
R
M
R
A
P
E
Y
S
T
P
E
I
Y
Q
Dog
Lupus familis
XP_534520
1337
150703
Y1124
M
R
M
R
A
P
E
Y
A
T
P
E
I
Y
Q
Cat
Felis silvestris
Mouse
Mus musculus
P35969
1333
149858
Y1124
M
R
M
R
T
P
E
Y
A
T
P
E
I
Y
Q
Rat
Rattus norvegicus
P53767
1336
150231
Y1124
M
R
M
R
T
P
E
Y
A
T
P
E
I
Y
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519611
1329
147097
F1124
T
R
M
R
A
P
E
F
A
T
A
E
I
Y
Q
Chicken
Gallus gallus
Q8QHL3
1327
149408
Q1117
T
R
M
R
A
P
E
Q
A
T
E
E
I
Y
Q
Frog
Xenopus laevis
Q91909
954
106841
N765
Y
Q
V
A
Q
G
M
N
F
L
A
S
K
N
C
Zebra Danio
Brachydanio rerio
Q8AXB3
1302
146931
Y1105
T
R
M
K
A
P
E
Y
S
S
S
E
I
Y
Q
Tiger Blowfish
Takifugu rubipres
Q8AXC6
984
110714
A795
L
L
T
Q
G
R
V
A
K
I
C
D
F
G
L
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
88.2
89.9
N.A.
81.6
82.3
N.A.
71.9
68.9
25.6
44.1
28.7
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.9
89.2
95.3
N.A.
90.3
90.7
N.A.
83.9
80.4
41.7
61.3
45.1
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
73.3
73.3
0
73.3
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
86.6
80
13.3
86.6
20
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
64
0
0
10
46
0
19
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
10
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% D
% Glu:
0
0
0
0
0
0
82
0
0
0
10
82
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
10
10
0
0
0
10
0
0
% F
% Gly:
0
0
0
0
10
10
0
0
0
0
0
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
10
0
0
82
0
0
% I
% Lys:
0
0
0
10
0
0
0
0
10
0
0
0
10
0
0
% K
% Leu:
10
10
0
0
0
0
0
0
0
10
0
0
0
0
10
% L
% Met:
55
0
82
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
0
0
10
0
% N
% Pro:
0
0
0
0
0
82
0
0
0
0
55
0
0
0
0
% P
% Gln:
0
10
0
10
10
0
0
10
0
0
0
0
0
0
82
% Q
% Arg:
0
82
0
73
0
10
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
37
10
10
10
0
0
0
% S
% Thr:
28
0
10
0
19
0
0
0
0
73
0
0
0
0
0
% T
% Val:
0
0
10
0
0
0
10
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
64
0
0
0
0
0
82
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _