Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PSMC3 All Species: 18.18
Human Site: S9 Identified Species: 26.67
UniProt: P17980 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P17980 NP_002795.2 439 49204 S9 N L L P N I E S P V T R Q E K
Chimpanzee Pan troglodytes XP_508413 555 61671 S125 N L L P N L E S P V T R Q E K
Rhesus Macaque Macaca mulatta XP_001106497 439 49185 S9 N L L P N L E S P V T R Q E K
Dog Lupus familis XP_533187 402 44931 Q10 T V W D E A E Q D G I G E E V
Cat Felis silvestris
Mouse Mus musculus O88685 442 49474 S12 N L L P T P E S P V T R Q E K
Rat Rattus norvegicus Q63569 439 49142 S9 N L L P T P E S P V T R Q E K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90732 440 49185 D18 P G G G K K D D K D K K K K Y
Frog Xenopus laevis O42586 404 45258 R9 S T E E I I Q R T R L L D S E
Zebra Danio Brachydanio rerio NP_001002064 404 45291 R9 S T E E I V Q R T R L L D S E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P48601 439 49305 A11 N Q S A Q G G A G E K K D D K
Honey Bee Apis mellifera XP_392722 428 47609 S8 M A T L E D K S L W E D G E E
Nematode Worm Caenorhab. elegans O16368 443 49704 F8 M G Q Q Q S G F G G R G N D R
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002330164 423 47370 D8 M A T P M A E D S S F E D D Q
Maize Zea mays NP_001142386 430 47792 A8 M S S S G A P A P A A A M A V
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O04019 423 47019 D8 M A T A M A E D T S F E G D Q
Baker's Yeast Sacchar. cerevisiae P33297 434 48237 D8 M A T L E E L D A Q T L P G D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 78.9 99.7 91.5 N.A. 97.9 99.3 N.A. N.A. 40 90.8 90.4 N.A. 40 83.8 39.5 N.A.
Protein Similarity: 100 79 100 91.5 N.A. 98.6 99.5 N.A. N.A. 60.9 91.5 91.1 N.A. 60.5 91.1 59.5 N.A.
P-Site Identity: 100 93.3 93.3 13.3 N.A. 86.6 86.6 N.A. N.A. 0 6.6 0 N.A. 13.3 13.3 0 N.A.
P-Site Similarity: 100 100 100 26.6 N.A. 86.6 86.6 N.A. N.A. 26.6 26.6 26.6 N.A. 33.3 26.6 13.3 N.A.
Percent
Protein Identity: 74 75.6 N.A. 73.1 67.6 N.A.
Protein Similarity: 87 88.6 N.A. 85.4 84 N.A.
P-Site Identity: 13.3 6.6 N.A. 6.6 6.6 N.A.
P-Site Similarity: 26.6 13.3 N.A. 20 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 25 0 13 0 25 0 13 7 7 7 7 0 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 7 0 7 7 25 7 7 0 7 25 25 7 % D
% Glu: 0 0 13 13 19 7 50 0 0 7 7 13 7 44 19 % E
% Phe: 0 0 0 0 0 0 0 7 0 0 13 0 0 0 0 % F
% Gly: 0 13 7 7 7 7 13 0 13 13 0 13 13 7 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 13 13 0 0 0 0 7 0 0 0 0 % I
% Lys: 0 0 0 0 7 7 7 0 7 0 13 13 7 7 38 % K
% Leu: 0 32 32 13 0 13 7 0 7 0 13 19 0 0 0 % L
% Met: 38 0 0 0 13 0 0 0 0 0 0 0 7 0 0 % M
% Asn: 38 0 0 0 19 0 0 0 0 0 0 0 7 0 0 % N
% Pro: 7 0 0 38 0 13 7 0 38 0 0 0 7 0 0 % P
% Gln: 0 7 7 7 13 0 13 7 0 7 0 0 32 0 13 % Q
% Arg: 0 0 0 0 0 0 0 13 0 13 7 32 0 0 7 % R
% Ser: 13 7 13 7 0 7 0 38 7 13 0 0 0 13 0 % S
% Thr: 7 13 25 0 13 0 0 0 19 0 38 0 0 0 0 % T
% Val: 0 7 0 0 0 7 0 0 0 32 0 0 0 0 13 % V
% Trp: 0 0 7 0 0 0 0 0 0 7 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _