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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PSMC3
All Species:
45.76
Human Site:
T166
Identified Species:
67.11
UniProt:
P17980
Number Species:
15
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P17980
NP_002795.2
439
49204
T166
L
I
L
E
T
L
P
T
E
Y
D
S
R
V
K
Chimpanzee
Pan troglodytes
XP_508413
555
61671
T282
L
I
L
E
T
L
P
T
E
Y
D
S
R
V
K
Rhesus Macaque
Macaca mulatta
XP_001106497
439
49185
T166
L
I
L
E
T
L
P
T
E
Y
D
S
R
V
K
Dog
Lupus familis
XP_533187
402
44931
T150
L
I
L
E
T
L
P
T
E
Y
D
S
R
V
K
Cat
Felis silvestris
Mouse
Mus musculus
O88685
442
49474
T169
L
I
L
E
T
L
P
T
D
Y
D
S
R
V
K
Rat
Rattus norvegicus
Q63569
439
49142
T166
L
I
L
E
T
L
P
T
E
Y
D
S
R
V
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90732
440
49185
D165
A
V
I
G
V
L
M
D
D
T
D
P
L
V
T
Frog
Xenopus laevis
O42586
404
45258
T147
M
E
V
D
E
R
P
T
E
Q
Y
S
D
I
G
Zebra Danio
Brachydanio rerio
NP_001002064
404
45291
T147
M
E
V
D
E
R
P
T
E
Q
Y
S
D
I
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48601
439
49305
D164
A
V
V
G
V
L
S
D
D
T
D
P
M
V
T
Honey Bee
Apis mellifera
XP_392722
428
47609
A155
L
V
L
E
T
L
P
A
E
Y
D
A
R
V
K
Nematode Worm
Caenorhab. elegans
O16368
443
49704
D168
A
V
I
G
V
L
S
D
D
T
D
P
M
V
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002330164
423
47370
S150
L
I
L
D
T
L
P
S
E
Y
D
S
R
V
K
Maize
Zea mays
NP_001142386
430
47792
S157
L
I
L
D
T
L
P
S
E
Y
D
S
R
V
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04019
423
47019
S150
L
I
L
D
T
L
P
S
E
Y
D
S
R
V
K
Baker's Yeast
Sacchar. cerevisiae
P33297
434
48237
S161
L
I
L
D
T
L
P
S
E
F
D
S
R
V
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.9
99.7
91.5
N.A.
97.9
99.3
N.A.
N.A.
40
90.8
90.4
N.A.
40
83.8
39.5
N.A.
Protein Similarity:
100
79
100
91.5
N.A.
98.6
99.5
N.A.
N.A.
60.9
91.5
91.1
N.A.
60.5
91.1
59.5
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
100
N.A.
N.A.
20
26.6
26.6
N.A.
20
80
20
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
40
53.3
53.3
N.A.
40
93.3
40
N.A.
Percent
Protein Identity:
74
75.6
N.A.
73.1
67.6
N.A.
Protein Similarity:
87
88.6
N.A.
85.4
84
N.A.
P-Site Identity:
86.6
86.6
N.A.
86.6
80
N.A.
P-Site Similarity:
100
100
N.A.
100
100
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
0
0
0
0
0
0
7
0
0
0
7
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
38
0
0
0
19
25
0
88
0
13
0
0
% D
% Glu:
0
13
0
44
13
0
0
0
75
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% F
% Gly:
0
0
0
19
0
0
0
0
0
0
0
0
0
0
13
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
63
13
0
0
0
0
0
0
0
0
0
0
13
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
69
% K
% Leu:
69
0
69
0
0
88
0
0
0
0
0
0
7
0
0
% L
% Met:
13
0
0
0
0
0
7
0
0
0
0
0
13
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
82
0
0
0
0
19
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
13
0
0
0
0
0
0
69
0
0
% R
% Ser:
0
0
0
0
0
0
13
25
0
0
0
75
0
0
7
% S
% Thr:
0
0
0
0
69
0
0
50
0
19
0
0
0
0
13
% T
% Val:
0
25
19
0
19
0
0
0
0
0
0
0
0
88
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
63
13
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _