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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PSMC3
All Species:
26.97
Human Site:
Y420
Identified Species:
39.56
UniProt:
P17980
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P17980
NP_002795.2
439
49204
Y420
T
E
L
T
H
E
D
Y
M
E
G
I
L
E
V
Chimpanzee
Pan troglodytes
XP_508413
555
61671
Y536
T
E
L
T
H
E
D
Y
M
E
G
I
L
E
V
Rhesus Macaque
Macaca mulatta
XP_001106497
439
49185
Y420
T
E
L
T
H
E
D
Y
M
E
G
I
L
E
V
Dog
Lupus familis
XP_533187
402
44931
Y383
T
E
L
T
H
E
D
Y
M
E
G
I
L
E
V
Cat
Felis silvestris
Mouse
Mus musculus
O88685
442
49474
H423
T
E
L
T
H
E
D
H
M
E
G
I
L
E
V
Rat
Rattus norvegicus
Q63569
439
49142
Y420
T
E
L
T
H
E
D
Y
M
E
G
I
L
E
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90732
440
49185
F419
M
K
V
T
N
E
D
F
K
K
S
K
E
N
F
Frog
Xenopus laevis
O42586
404
45258
Y385
T
E
L
T
H
E
D
Y
M
E
G
I
L
E
V
Zebra Danio
Brachydanio rerio
NP_001002064
404
45291
Y385
T
E
L
N
H
E
D
Y
M
E
G
I
L
E
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48601
439
49305
F418
M
K
V
T
N
E
D
F
K
K
S
K
E
S
V
Honey Bee
Apis mellifera
XP_392722
428
47609
L409
T
A
V
T
H
E
D
L
M
E
A
I
N
E
V
Nematode Worm
Caenorhab. elegans
O16368
443
49704
F422
M
R
V
T
M
E
D
F
Q
K
S
K
E
N
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002330164
423
47370
F404
T
E
V
N
H
E
D
F
N
E
G
I
I
Q
V
Maize
Zea mays
NP_001142386
430
47792
F411
T
E
V
T
H
E
D
F
N
E
G
I
V
Q
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04019
423
47019
F404
T
E
V
N
H
E
D
F
N
E
G
I
I
Q
V
Baker's Yeast
Sacchar. cerevisiae
P33297
434
48237
F415
S
S
V
K
H
E
D
F
V
E
G
I
S
E
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.9
99.7
91.5
N.A.
97.9
99.3
N.A.
N.A.
40
90.8
90.4
N.A.
40
83.8
39.5
N.A.
Protein Similarity:
100
79
100
91.5
N.A.
98.6
99.5
N.A.
N.A.
60.9
91.5
91.1
N.A.
60.5
91.1
59.5
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
100
N.A.
N.A.
20
100
93.3
N.A.
26.6
66.6
26.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
53.3
100
93.3
N.A.
60
73.3
46.6
N.A.
Percent
Protein Identity:
74
75.6
N.A.
73.1
67.6
N.A.
Protein Similarity:
87
88.6
N.A.
85.4
84
N.A.
P-Site Identity:
60
66.6
N.A.
60
53.3
N.A.
P-Site Similarity:
86.6
93.3
N.A.
86.6
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
0
0
0
0
0
0
7
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
100
0
0
0
0
0
0
0
0
% D
% Glu:
0
69
0
0
0
100
0
0
0
82
0
0
19
63
0
% E
% Phe:
0
0
0
0
0
0
0
44
0
0
0
0
0
0
7
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
75
0
0
0
0
% G
% His:
0
0
0
0
82
0
0
7
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
82
13
0
0
% I
% Lys:
0
13
0
7
0
0
0
0
13
19
0
19
0
0
0
% K
% Leu:
0
0
50
0
0
0
0
7
0
0
0
0
50
0
0
% L
% Met:
19
0
0
0
7
0
0
0
57
0
0
0
0
0
0
% M
% Asn:
0
0
0
19
13
0
0
0
19
0
0
0
7
13
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
7
0
0
0
0
19
0
% Q
% Arg:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
7
7
0
0
0
0
0
0
0
0
19
0
7
7
0
% S
% Thr:
75
0
0
75
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
50
0
0
0
0
0
7
0
0
0
7
0
94
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
44
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _