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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PSMC3
All Species:
53.03
Human Site:
Y438
Identified Species:
77.78
UniProt:
P17980
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P17980
NP_002795.2
439
49204
Y438
K
K
A
N
L
Q
Y
Y
A
_
_
_
_
_
_
Chimpanzee
Pan troglodytes
XP_508413
555
61671
Y554
K
K
A
N
L
Q
Y
Y
A
_
_
_
_
_
_
Rhesus Macaque
Macaca mulatta
XP_001106497
439
49185
Y438
K
K
A
N
L
Q
Y
Y
A
_
_
_
_
_
_
Dog
Lupus familis
XP_533187
402
44931
Y401
K
K
A
N
L
Q
Y
Y
A
_
_
_
_
_
_
Cat
Felis silvestris
Mouse
Mus musculus
O88685
442
49474
Y441
K
K
A
N
L
Q
Y
Y
A
_
_
_
_
_
_
Rat
Rattus norvegicus
Q63569
439
49142
Y438
K
K
A
N
L
Q
Y
Y
A
_
_
_
_
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90732
440
49185
L438
T
E
G
T
P
E
G
L
Y
L
_
_
_
_
_
Frog
Xenopus laevis
O42586
404
45258
Y403
K
K
A
N
L
Q
Y
Y
A
_
_
_
_
_
_
Zebra Danio
Brachydanio rerio
NP_001002064
404
45291
Y403
K
K
A
N
L
Q
Y
Y
A
_
_
_
_
_
_
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48601
439
49305
L437
K
E
G
T
P
E
G
L
Y
L
_
_
_
_
_
Honey Bee
Apis mellifera
XP_392722
428
47609
Y427
K
K
A
N
L
N
Y
Y
A
_
_
_
_
_
_
Nematode Worm
Caenorhab. elegans
O16368
443
49704
Y442
E
G
A
P
E
E
L
Y
L
_
_
_
_
_
_
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002330164
423
47370
Y422
K
K
A
S
L
N
Y
Y
A
_
_
_
_
_
_
Maize
Zea mays
NP_001142386
430
47792
Y429
K
K
S
S
L
N
Y
Y
A
_
_
_
_
_
_
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04019
423
47019
Y422
K
K
A
S
L
N
Y
Y
A
_
_
_
_
_
_
Baker's Yeast
Sacchar. cerevisiae
P33297
434
48237
Y433
K
S
K
S
V
S
F
Y
A
_
_
_
_
_
_
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.9
99.7
91.5
N.A.
97.9
99.3
N.A.
N.A.
40
90.8
90.4
N.A.
40
83.8
39.5
N.A.
Protein Similarity:
100
79
100
91.5
N.A.
98.6
99.5
N.A.
N.A.
60.9
91.5
91.1
N.A.
60.5
91.1
59.5
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
0
100
100
N.A.
10
88.8
22.2
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
20
100
100
N.A.
30
88.8
44.4
N.A.
Percent
Protein Identity:
74
75.6
N.A.
73.1
67.6
N.A.
Protein Similarity:
87
88.6
N.A.
85.4
84
N.A.
P-Site Identity:
77.7
66.6
N.A.
77.7
33.3
N.A.
P-Site Similarity:
88.8
88.8
N.A.
88.8
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
75
0
0
0
0
0
82
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
7
13
0
0
7
19
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% F
% Gly:
0
7
13
0
0
0
13
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
88
75
7
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
75
0
7
13
7
13
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
57
0
25
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
7
13
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
50
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
7
7
25
0
7
0
0
0
0
0
0
0
0
0
% S
% Thr:
7
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
75
88
13
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
88
100
100
100
100
100
% _