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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TCP1
All Species:
10.3
Human Site:
S491
Identified Species:
15.11
UniProt:
P17987
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P17987
NP_110379.2
556
60344
S491
K
W
I
G
L
D
L
S
N
G
K
P
R
D
N
Chimpanzee
Pan troglodytes
XP_001149107
534
57962
S469
K
W
I
G
L
D
L
S
N
G
K
P
R
D
N
Rhesus Macaque
Macaca mulatta
XP_001098115
556
60283
S491
K
W
I
G
L
D
L
S
N
G
K
P
R
D
N
Dog
Lupus familis
XP_541181
556
60235
I491
K
W
I
G
L
D
L
I
N
G
K
P
R
D
N
Cat
Felis silvestris
Mouse
Mus musculus
P11983
556
60430
V491
K
W
I
G
L
D
L
V
H
G
K
P
R
D
N
Rat
Rattus norvegicus
P28480
556
60341
V491
K
W
I
G
L
D
L
V
H
G
K
P
R
D
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508499
535
58000
V469
K
W
I
G
L
D
L
V
N
G
K
P
R
D
N
Chicken
Gallus gallus
NP_001006405
558
60448
V494
K
W
I
G
L
D
L
V
N
G
K
P
R
D
N
Frog
Xenopus laevis
NP_001080978
555
60156
L491
K
W
I
G
L
D
L
L
N
G
K
P
R
D
N
Zebra Danio
Brachydanio rerio
NP_571305
556
59968
V492
K
W
I
G
L
D
L
V
N
G
K
P
R
D
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P12613
557
59538
T489
E
R
S
D
L
K
W
T
G
L
D
L
I
E
G
Honey Bee
Apis mellifera
XP_392660
557
59923
A484
S
Q
T
K
A
D
L
A
D
L
K
W
V
G
L
Nematode Worm
Caenorhab. elegans
P41988
549
58784
Q484
A
Q
L
I
P
Q
L
Q
H
L
K
W
A
G
L
Sea Urchin
Strong. purpuratus
XP_780270
561
60078
V493
K
W
I
G
L
D
L
V
N
G
V
V
R
D
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P28769
545
59211
A481
H
H
T
A
Q
T
K
A
D
K
K
H
Y
S
S
Baker's Yeast
Sacchar. cerevisiae
P12612
559
60462
K493
M
A
K
P
E
D
V
K
R
R
S
Y
R
N
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96
99.6
97.6
N.A.
96.4
97.6
N.A.
91.7
90.6
89.2
86.8
N.A.
73.2
74.6
67.6
72.7
Protein Similarity:
100
96
99.6
99
N.A.
98.3
99
N.A.
94.4
96.7
95.8
94.2
N.A.
85.2
85.2
81.6
83.9
P-Site Identity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
93.3
93.3
93.3
93.3
N.A.
6.6
20
13.3
80
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
93.3
93.3
93.3
93.3
N.A.
26.6
33.3
26.6
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
64.5
62.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
82.1
79.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
7
7
0
0
13
0
0
0
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
7
0
82
0
0
13
0
7
0
0
69
0
% D
% Glu:
7
0
0
0
7
0
0
0
0
0
0
0
0
7
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
69
0
0
0
0
7
69
0
0
0
13
7
% G
% His:
7
7
0
0
0
0
0
0
19
0
0
7
0
0
0
% H
% Ile:
0
0
69
7
0
0
0
7
0
0
0
0
7
0
0
% I
% Lys:
69
0
7
7
0
7
7
7
0
7
82
0
0
0
0
% K
% Leu:
0
0
7
0
75
0
82
7
0
19
0
7
0
0
13
% L
% Met:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
57
0
0
0
0
7
69
% N
% Pro:
0
0
0
7
7
0
0
0
0
0
0
63
0
0
0
% P
% Gln:
0
13
0
0
7
7
0
7
0
0
0
0
0
0
0
% Q
% Arg:
0
7
0
0
0
0
0
0
7
7
0
0
75
0
0
% R
% Ser:
7
0
7
0
0
0
0
19
0
0
7
0
0
7
7
% S
% Thr:
0
0
13
0
0
7
0
7
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
7
38
0
0
7
7
7
0
0
% V
% Trp:
0
69
0
0
0
0
7
0
0
0
0
13
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
7
7
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _