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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALOX12
All Species:
18.79
Human Site:
S249
Identified Species:
59.05
UniProt:
P18054
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P18054
NP_000688.2
663
75694
S249
R
R
S
T
S
L
P
S
R
L
V
L
P
S
G
Chimpanzee
Pan troglodytes
XP_511984
658
75020
S249
R
R
S
T
S
L
P
S
R
L
V
L
P
S
G
Rhesus Macaque
Macaca mulatta
XP_001104192
663
75540
S249
R
R
S
T
S
L
P
S
R
L
A
L
P
S
G
Dog
Lupus familis
XP_536613
663
75328
S249
R
R
S
A
C
L
P
S
R
L
V
L
P
P
G
Cat
Felis silvestris
Mouse
Mus musculus
P39655
663
75371
S249
R
R
S
T
S
L
P
S
R
L
V
L
P
S
G
Rat
Rattus norvegicus
Q02759
663
75373
A250
K
R
S
T
C
L
P
A
R
L
V
F
P
P
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_955912
670
76988
S254
T
R
L
K
K
V
P
S
N
F
L
V
T
G
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9CAG3
917
104497
I440
E
L
L
K
E
L
P
I
R
S
N
L
D
P
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.9
96.3
85.9
N.A.
85.5
58.6
N.A.
N.A.
N.A.
N.A.
46.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
93.9
98.1
92.1
N.A.
91.2
74.6
N.A.
N.A.
N.A.
N.A.
64.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
80
N.A.
100
66.6
N.A.
N.A.
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
80
N.A.
100
80
N.A.
N.A.
N.A.
N.A.
40
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
13
0
0
0
13
0
0
13
0
0
0
13
% A
% Cys:
0
0
0
0
25
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
13
% D
% Glu:
13
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
13
0
13
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
75
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% I
% Lys:
13
0
0
25
13
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
13
25
0
0
88
0
0
0
75
13
75
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
13
0
13
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
100
0
0
0
0
0
75
38
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
63
88
0
0
0
0
0
0
88
0
0
0
0
0
0
% R
% Ser:
0
0
75
0
50
0
0
75
0
13
0
0
0
50
0
% S
% Thr:
13
0
0
63
0
0
0
0
0
0
0
0
13
0
0
% T
% Val:
0
0
0
0
0
13
0
0
0
0
63
13
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _