KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERCC2
All Species:
21.52
Human Site:
S578
Identified Species:
43.03
UniProt:
P18074
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P18074
NP_000391.1
760
86909
S578
T
Q
D
G
A
E
T
S
V
A
L
E
K
Y
Q
Chimpanzee
Pan troglodytes
XP_001164105
760
86877
S578
T
Q
D
G
A
E
T
S
V
A
L
E
K
Y
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_541562
641
72772
M483
V
T
M
A
T
F
T
M
T
L
A
R
V
C
L
Cat
Felis silvestris
Mouse
Mus musculus
O08811
760
86810
S578
T
Q
D
G
A
E
T
S
V
A
L
E
K
Y
Q
Rat
Rattus norvegicus
Q5RJZ1
1274
141760
V601
N
K
G
S
F
S
E
V
I
D
A
Y
Y
Q
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q3YK19
1252
140086
L749
K
S
D
F
D
E
L
L
K
I
Y
Y
D
A
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W484
985
109665
T600
P
R
S
K
D
Q
F
T
S
T
M
E
E
F
Y
Honey Bee
Apis mellifera
XP_396155
772
88880
S591
T
Q
D
S
A
E
T
S
L
A
L
I
N
Y
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780825
683
77496
I525
I
R
N
Y
G
N
L
I
V
E
L
S
G
I
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8W4M7
758
86217
T578
T
Q
D
V
V
E
T
T
L
A
L
D
N
Y
R
Baker's Yeast
Sacchar. cerevisiae
P06839
778
89768
S580
T
P
D
A
Q
E
T
S
L
A
L
E
T
Y
R
Red Bread Mold
Neurospora crassa
A7UXD4
1073
119198
H860
Q
K
Y
S
D
V
I
H
S
E
V
R
P
L
S
Conservation
Percent
Protein Identity:
100
99.7
N.A.
82.3
N.A.
97.3
20.7
N.A.
N.A.
20.2
N.A.
N.A.
N.A.
20
70.3
N.A.
67.6
Protein Similarity:
100
100
N.A.
83.4
N.A.
98.9
33.2
N.A.
N.A.
33.7
N.A.
N.A.
N.A.
36.2
84.8
N.A.
80.1
P-Site Identity:
100
100
N.A.
6.6
N.A.
100
6.6
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
6.6
66.6
N.A.
13.3
P-Site Similarity:
100
100
N.A.
6.6
N.A.
100
20
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
46.6
73.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
54.7
51.1
21.1
Protein Similarity:
N.A.
N.A.
N.A.
73.2
71.3
35.7
P-Site Identity:
N.A.
N.A.
N.A.
53.3
60
0
P-Site Similarity:
N.A.
N.A.
N.A.
80
73.3
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
17
34
0
0
0
0
50
17
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% C
% Asp:
0
0
59
0
25
0
0
0
0
9
0
9
9
0
0
% D
% Glu:
0
0
0
0
0
59
9
0
0
17
0
42
9
0
0
% E
% Phe:
0
0
0
9
9
9
9
0
0
0
0
0
0
9
0
% F
% Gly:
0
0
9
25
9
0
0
0
0
0
0
0
9
0
0
% G
% His:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% H
% Ile:
9
0
0
0
0
0
9
9
9
9
0
9
0
9
17
% I
% Lys:
9
17
0
9
0
0
0
0
9
0
0
0
25
0
0
% K
% Leu:
0
0
0
0
0
0
17
9
25
9
59
0
0
9
9
% L
% Met:
0
0
9
0
0
0
0
9
0
0
9
0
0
0
0
% M
% Asn:
9
0
9
0
0
9
0
0
0
0
0
0
17
0
0
% N
% Pro:
9
9
0
0
0
0
0
0
0
0
0
0
9
0
0
% P
% Gln:
9
42
0
0
9
9
0
0
0
0
0
0
0
9
34
% Q
% Arg:
0
17
0
0
0
0
0
0
0
0
0
17
0
0
17
% R
% Ser:
0
9
9
25
0
9
0
42
17
0
0
9
0
0
9
% S
% Thr:
50
9
0
0
9
0
59
17
9
9
0
0
9
0
0
% T
% Val:
9
0
0
9
9
9
0
9
34
0
9
0
9
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
9
0
0
0
0
0
0
9
17
9
50
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _