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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERCC2
All Species:
23.03
Human Site:
T653
Identified Species:
46.06
UniProt:
P18074
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P18074
NP_000391.1
760
86909
T653
I
R
E
N
D
F
L
T
F
D
A
M
R
H
A
Chimpanzee
Pan troglodytes
XP_001164105
760
86877
T653
I
R
E
N
D
F
L
T
F
D
A
M
R
H
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_541562
641
72772
L558
S
W
Y
E
Q
G
I
L
E
N
I
Q
R
N
K
Cat
Felis silvestris
Mouse
Mus musculus
O08811
760
86810
T653
I
R
E
N
D
F
L
T
F
D
A
M
R
H
A
Rat
Rattus norvegicus
Q5RJZ1
1274
141760
C676
R
S
R
V
G
G
Q
C
L
S
G
Q
E
W
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q3YK19
1252
140086
S824
T
R
G
L
L
P
G
S
Q
W
Y
E
I
Q
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W484
985
109665
G675
R
E
N
Q
L
L
S
G
Q
E
W
Y
N
L
D
Honey Bee
Apis mellifera
XP_396155
772
88880
T666
I
R
E
N
D
F
L
T
F
D
A
M
R
H
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780825
683
77496
V600
R
G
A
I
L
L
S
V
A
R
G
K
V
S
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8W4M7
758
86217
T653
I
K
E
G
D
F
L
T
F
D
A
L
R
Q
A
Baker's Yeast
Sacchar. cerevisiae
P06839
778
89768
S655
I
R
E
N
D
F
L
S
F
D
A
M
R
H
A
Red Bread Mold
Neurospora crassa
A7UXD4
1073
119198
Q935
K
R
Y
T
A
S
Q
Q
T
S
T
A
T
A
P
Conservation
Percent
Protein Identity:
100
99.7
N.A.
82.3
N.A.
97.3
20.7
N.A.
N.A.
20.2
N.A.
N.A.
N.A.
20
70.3
N.A.
67.6
Protein Similarity:
100
100
N.A.
83.4
N.A.
98.9
33.2
N.A.
N.A.
33.7
N.A.
N.A.
N.A.
36.2
84.8
N.A.
80.1
P-Site Identity:
100
100
N.A.
6.6
N.A.
100
0
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
0
100
N.A.
0
P-Site Similarity:
100
100
N.A.
26.6
N.A.
100
0
N.A.
N.A.
20
N.A.
N.A.
N.A.
6.6
100
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
54.7
51.1
21.1
Protein Similarity:
N.A.
N.A.
N.A.
73.2
71.3
35.7
P-Site Identity:
N.A.
N.A.
N.A.
73.3
93.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
86.6
100
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
9
0
0
0
9
0
50
9
0
9
59
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
50
0
0
0
0
50
0
0
0
0
9
% D
% Glu:
0
9
50
9
0
0
0
0
9
9
0
9
9
0
9
% E
% Phe:
0
0
0
0
0
50
0
0
50
0
0
0
0
0
0
% F
% Gly:
0
9
9
9
9
17
9
9
0
0
17
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
42
0
% H
% Ile:
50
0
0
9
0
0
9
0
0
0
9
0
9
0
0
% I
% Lys:
9
9
0
0
0
0
0
0
0
0
0
9
0
0
9
% K
% Leu:
0
0
0
9
25
17
50
9
9
0
0
9
0
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
42
0
0
0
% M
% Asn:
0
0
9
42
0
0
0
0
0
9
0
0
9
9
0
% N
% Pro:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
9
% P
% Gln:
0
0
0
9
9
0
17
9
17
0
0
17
0
17
0
% Q
% Arg:
25
59
9
0
0
0
0
0
0
9
0
0
59
0
0
% R
% Ser:
9
9
0
0
0
9
17
17
0
17
0
0
0
9
0
% S
% Thr:
9
0
0
9
0
0
0
42
9
0
9
0
9
0
0
% T
% Val:
0
0
0
9
0
0
0
9
0
0
0
0
9
0
0
% V
% Trp:
0
9
0
0
0
0
0
0
0
9
9
0
0
9
0
% W
% Tyr:
0
0
17
0
0
0
0
0
0
0
9
9
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _