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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERCC2
All Species:
20.91
Human Site:
T702
Identified Species:
41.82
UniProt:
P18074
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P18074
NP_000391.1
760
86909
T702
R
W
I
Q
E
H
L
T
D
A
N
L
N
L
T
Chimpanzee
Pan troglodytes
XP_001164105
760
86877
T702
R
W
I
Q
E
H
L
T
D
A
N
L
N
L
T
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_541562
641
72772
N590
K
Y
Q
E
A
C
E
N
G
R
G
A
I
L
L
Cat
Felis silvestris
Mouse
Mus musculus
O08811
760
86810
T702
R
W
I
Q
E
H
L
T
D
S
N
L
N
L
T
Rat
Rattus norvegicus
Q5RJZ1
1274
141760
S855
A
S
E
E
Q
A
L
S
S
S
T
P
S
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q3YK19
1252
140086
F1168
P
T
V
A
D
D
L
F
V
I
S
T
S
K
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W484
985
109665
G729
K
W
I
R
G
H
L
G
D
R
P
Q
C
S
P
Honey Bee
Apis mellifera
XP_396155
772
88880
T715
K
W
I
Q
E
H
L
T
D
S
L
C
N
L
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780825
683
77496
R632
P
Y
V
Y
T
Q
S
R
I
L
K
A
R
L
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8W4M7
758
86217
R702
G
W
I
L
S
H
L
R
D
A
H
L
N
L
S
Baker's Yeast
Sacchar. cerevisiae
P06839
778
89768
S702
K
W
I
A
Q
G
L
S
D
A
D
L
N
L
S
Red Bread Mold
Neurospora crassa
A7UXD4
1073
119198
T991
H
Q
F
Y
E
N
A
T
L
R
A
V
N
Q
S
Conservation
Percent
Protein Identity:
100
99.7
N.A.
82.3
N.A.
97.3
20.7
N.A.
N.A.
20.2
N.A.
N.A.
N.A.
20
70.3
N.A.
67.6
Protein Similarity:
100
100
N.A.
83.4
N.A.
98.9
33.2
N.A.
N.A.
33.7
N.A.
N.A.
N.A.
36.2
84.8
N.A.
80.1
P-Site Identity:
100
100
N.A.
6.6
N.A.
93.3
13.3
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
33.3
66.6
N.A.
6.6
P-Site Similarity:
100
100
N.A.
26.6
N.A.
100
46.6
N.A.
N.A.
40
N.A.
N.A.
N.A.
46.6
86.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
54.7
51.1
21.1
Protein Similarity:
N.A.
N.A.
N.A.
73.2
71.3
35.7
P-Site Identity:
N.A.
N.A.
N.A.
60
53.3
20
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
86.6
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
17
9
9
9
0
0
34
9
17
0
0
0
% A
% Cys:
0
0
0
0
0
9
0
0
0
0
0
9
9
0
0
% C
% Asp:
0
0
0
0
9
9
0
0
59
0
9
0
0
0
0
% D
% Glu:
0
0
9
17
42
0
9
0
0
0
0
0
0
0
9
% E
% Phe:
0
0
9
0
0
0
0
9
0
0
0
0
0
0
0
% F
% Gly:
9
0
0
0
9
9
0
9
9
0
9
0
0
0
0
% G
% His:
9
0
0
0
0
50
0
0
0
0
9
0
0
0
0
% H
% Ile:
0
0
59
0
0
0
0
0
9
9
0
0
9
0
0
% I
% Lys:
34
0
0
0
0
0
0
0
0
0
9
0
0
9
0
% K
% Leu:
0
0
0
9
0
0
75
0
9
9
9
42
0
75
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
9
0
9
0
0
25
0
59
0
0
% N
% Pro:
17
0
0
0
0
0
0
0
0
0
9
9
0
0
9
% P
% Gln:
0
9
9
34
17
9
0
0
0
0
0
9
0
9
0
% Q
% Arg:
25
0
0
9
0
0
0
17
0
25
0
0
9
0
9
% R
% Ser:
0
9
0
0
9
0
9
17
9
25
9
0
17
9
34
% S
% Thr:
0
9
0
0
9
0
0
42
0
0
9
9
0
0
34
% T
% Val:
0
0
17
0
0
0
0
0
9
0
0
9
0
0
0
% V
% Trp:
0
59
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
17
0
17
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _