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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERCC2
All Species:
26.06
Human Site:
Y18
Identified Species:
52.12
UniProt:
P18074
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P18074
NP_000391.1
760
86909
Y18
Y
F
P
Y
D
Y
I
Y
P
E
Q
F
S
Y
M
Chimpanzee
Pan troglodytes
XP_001164105
760
86877
Y18
Y
F
P
Y
D
Y
I
Y
P
E
Q
F
S
Y
M
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_541562
641
72772
Cat
Felis silvestris
Mouse
Mus musculus
O08811
760
86810
Y18
Y
F
P
Y
D
Y
I
Y
P
E
Q
F
S
Y
M
Rat
Rattus norvegicus
Q5RJZ1
1274
141760
Y18
V
D
F
P
F
Q
P
Y
P
C
Q
Q
E
Y
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q3YK19
1252
140086
Y22
I
M
F
P
C
K
A
Y
P
S
Q
L
A
M
M
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W484
985
109665
Y18
V
H
F
P
F
E
P
Y
P
V
Q
R
A
Y
M
Honey Bee
Apis mellifera
XP_396155
772
88880
Y31
Y
F
P
Y
D
Y
I
Y
P
E
Q
Y
A
Y
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780825
683
77496
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8W4M7
758
86217
Y18
Y
F
P
Y
D
N
I
Y
P
E
Q
Y
E
Y
M
Baker's Yeast
Sacchar. cerevisiae
P06839
778
89768
Y18
L
F
P
Y
P
K
I
Y
P
E
Q
Y
N
Y
M
Red Bread Mold
Neurospora crassa
A7UXD4
1073
119198
R178
T
W
L
R
N
H
K
R
L
Q
F
D
S
E
I
Conservation
Percent
Protein Identity:
100
99.7
N.A.
82.3
N.A.
97.3
20.7
N.A.
N.A.
20.2
N.A.
N.A.
N.A.
20
70.3
N.A.
67.6
Protein Similarity:
100
100
N.A.
83.4
N.A.
98.9
33.2
N.A.
N.A.
33.7
N.A.
N.A.
N.A.
36.2
84.8
N.A.
80.1
P-Site Identity:
100
100
N.A.
0
N.A.
100
33.3
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
33.3
86.6
N.A.
0
P-Site Similarity:
100
100
N.A.
0
N.A.
100
33.3
N.A.
N.A.
33.3
N.A.
N.A.
N.A.
40
100
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
54.7
51.1
21.1
Protein Similarity:
N.A.
N.A.
N.A.
73.2
71.3
35.7
P-Site Identity:
N.A.
N.A.
N.A.
80
66.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
86.6
80
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
9
0
0
0
0
0
25
0
0
% A
% Cys:
0
0
0
0
9
0
0
0
0
9
0
0
0
0
0
% C
% Asp:
0
9
0
0
42
0
0
0
0
0
0
9
0
0
0
% D
% Glu:
0
0
0
0
0
9
0
0
0
50
0
0
17
9
0
% E
% Phe:
0
50
25
0
17
0
0
0
0
0
9
25
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
9
0
0
0
9
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
0
0
0
0
50
0
0
0
0
0
0
0
9
% I
% Lys:
0
0
0
0
0
17
9
0
0
0
0
0
0
0
0
% K
% Leu:
9
0
9
0
0
0
0
0
9
0
0
9
0
0
0
% L
% Met:
0
9
0
0
0
0
0
0
0
0
0
0
0
9
75
% M
% Asn:
0
0
0
0
9
9
0
0
0
0
0
0
9
0
0
% N
% Pro:
0
0
50
25
9
0
17
0
75
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
9
0
0
0
9
75
9
0
0
0
% Q
% Arg:
0
0
0
9
0
0
0
9
0
0
0
9
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
9
0
0
34
0
0
% S
% Thr:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
17
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% V
% Trp:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
42
0
0
50
0
34
0
75
0
0
0
25
0
67
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _