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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BMP7 All Species: 35.45
Human Site: Y420 Identified Species: 70.91
UniProt: P18075 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P18075 NP_001710.1 431 49313 Y420 S N V I L K K Y R N M V V R A
Chimpanzee Pan troglodytes XP_001169955 412 46803 A405 A A R P P D P A A S K L G P E
Rhesus Macaque Macaca mulatta XP_001089138 436 49863 Y425 S N V I L K K Y R N M V V R A
Dog Lupus familis XP_534462 429 49032 Y418 S N V I L K K Y R N M V V R A
Cat Felis silvestris
Mouse Mus musculus P23359 430 49180 Y419 S N V I L K K Y R N M V V R A
Rat Rattus norvegicus Q04906 506 56204 Y495 S N V I L K K Y R N M V V R A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510324 430 49386 Y419 S N V I L K K Y R N M V V R A
Chicken Gallus gallus Q90752 405 46039 V398 L K N Y Q E M V V E G C G C R
Frog Xenopus laevis P30886 426 48946 Y415 A N V I L K K Y K N M V V Q A
Zebra Danio Brachydanio rerio P35621 355 40183 V348 L R H Y E D M V V D E C G C R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P27091 455 51669 Y444 E N V N L K K Y R N M I V K S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus P48969 461 51863 Y450 R N V V L K K Y K N M V V R A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89.5 97.4 96.5 N.A. 97.4 55.9 N.A. 90.7 30.3 59.6 30.3 N.A. 34.5 N.A. N.A. 38.3
Protein Similarity: 100 91.1 98.1 97.2 N.A. 98.6 68.7 N.A. 94.4 46.6 77.7 46.6 N.A. 52.7 N.A. N.A. 57.2
P-Site Identity: 100 0 100 100 N.A. 100 100 N.A. 100 0 80 0 N.A. 66.6 N.A. N.A. 80
P-Site Similarity: 100 20 100 100 N.A. 100 100 N.A. 100 6.6 100 6.6 N.A. 86.6 N.A. N.A. 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 9 0 0 0 0 0 9 9 0 0 0 0 0 67 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 17 0 17 0 % C
% Asp: 0 0 0 0 0 17 0 0 0 9 0 0 0 0 0 % D
% Glu: 9 0 0 0 9 9 0 0 0 9 9 0 0 0 9 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 9 0 25 0 0 % G
% His: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 59 0 0 0 0 0 0 0 9 0 0 0 % I
% Lys: 0 9 0 0 0 75 75 0 17 0 9 0 0 9 0 % K
% Leu: 17 0 0 0 75 0 0 0 0 0 0 9 0 0 0 % L
% Met: 0 0 0 0 0 0 17 0 0 0 75 0 0 0 0 % M
% Asn: 0 75 9 9 0 0 0 0 0 75 0 0 0 0 0 % N
% Pro: 0 0 0 9 9 0 9 0 0 0 0 0 0 9 0 % P
% Gln: 0 0 0 0 9 0 0 0 0 0 0 0 0 9 0 % Q
% Arg: 9 9 9 0 0 0 0 0 59 0 0 0 0 59 17 % R
% Ser: 50 0 0 0 0 0 0 0 0 9 0 0 0 0 9 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 75 9 0 0 0 17 17 0 0 67 75 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 17 0 0 0 75 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _