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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ITGB5
All Species:
24.85
Human Site:
S770
Identified Species:
49.7
UniProt:
P18084
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P18084
NP_002204.2
799
88054
S770
R
A
R
Y
E
M
A
S
N
P
L
Y
R
K
P
Chimpanzee
Pan troglodytes
XP_516706
899
98662
S870
R
A
R
Y
E
M
A
S
N
P
L
Y
R
K
P
Rhesus Macaque
Macaca mulatta
XP_001113909
799
87949
S770
R
A
R
Y
E
M
A
S
N
P
L
Y
R
K
P
Dog
Lupus familis
XP_851245
819
89576
S790
R
A
R
Y
E
M
A
S
N
P
L
Y
R
K
P
Cat
Felis silvestris
Mouse
Mus musculus
O70309
798
87890
S770
R
A
R
Y
E
M
A
S
N
P
L
Y
R
K
P
Rat
Rattus norvegicus
Q6AYF4
787
85940
T757
K
A
K
W
Q
T
G
T
N
P
L
Y
R
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512659
789
86367
T758
K
A
K
W
Q
T
G
T
N
P
L
Y
R
G
S
Chicken
Gallus gallus
P07228
803
88535
E774
E
F
A
K
F
E
K
E
K
M
N
A
K
W
D
Frog
Xenopus laevis
P12606
798
88149
E769
E
F
A
K
F
E
K
E
K
M
N
A
K
W
D
Zebra Danio
Brachydanio rerio
NP_001076305
823
91335
M794
R
S
R
A
R
Y
E
M
A
S
N
P
V
Y
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P11584
846
92638
E817
E
F
A
R
F
E
K
E
R
M
N
A
K
W
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q27874
809
90119
M781
T
F
N
N
E
R
L
M
A
K
W
D
T
N
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.3
98.6
86.4
N.A.
91.4
48
N.A.
47.1
42.7
43
68.8
N.A.
38
N.A.
38.4
N.A.
Protein Similarity:
100
88.6
99.5
90.8
N.A.
95.9
64.8
N.A.
64.7
59.6
60.3
79.9
N.A.
54.2
N.A.
54.6
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
40
N.A.
40
0
0
13.3
N.A.
0
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
73.3
N.A.
73.3
6.6
6.6
20
N.A.
6.6
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
59
25
9
0
0
42
0
17
0
0
25
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
25
% D
% Glu:
25
0
0
0
50
25
9
25
0
0
0
0
0
0
9
% E
% Phe:
0
34
0
0
25
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
17
0
0
0
0
0
0
17
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
17
0
17
17
0
0
25
0
17
9
0
0
25
42
9
% K
% Leu:
0
0
0
0
0
0
9
0
0
0
59
0
0
0
0
% L
% Met:
0
0
0
0
0
42
0
17
0
25
0
0
0
0
0
% M
% Asn:
0
0
9
9
0
0
0
0
59
0
34
0
0
9
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
59
0
9
0
0
42
% P
% Gln:
0
0
0
0
17
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
50
0
50
9
9
9
0
0
9
0
0
0
59
0
0
% R
% Ser:
0
9
0
0
0
0
0
42
0
9
0
0
0
0
17
% S
% Thr:
9
0
0
0
0
17
0
17
0
0
0
0
9
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% V
% Trp:
0
0
0
17
0
0
0
0
0
0
9
0
0
25
0
% W
% Tyr:
0
0
0
42
0
9
0
0
0
0
0
59
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _